Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines (Q31793569)

3 July 2017

title

Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines (English)

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3 July 2017

4

Abbas AK

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3 July 2017

Kane LP

1

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3 July 2017

Andres PG

series ordinal

2

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3 July 2017

Howland KC

series ordinal

3

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3 July 2017

Weiss A

series ordinal

5

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3 July 2017

language of work or name

English

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publication date

1 January 2001

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3 July 2017

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3 July 2017

volume

2

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3 July 2017

issue

1

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3 July 2017

page(s)

37-44

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CD28/B7 system of T cell costimulation

3 July 2017

cites work

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Expression of bcl-X(L) restores cell survival, but not proliferation off effector differentiation, in CD28-deficient T lymphocytes

21 January 2018

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Differential T cell costimulatory requirements in CD28-deficient mice

21 January 2018

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CD28: a signalling perspective.

21 January 2018

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CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites

21 January 2018

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The B7 and CD28 receptor families

21 January 2018

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Signal transmission between the plasma membrane and nucleus of T lymphocytes

21 January 2018

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Transcriptional regulation of the IL-2 gene

21 January 2018

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Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

21 January 2018

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Coordinate transactivation of the interleukin-2 CD28 response element by c-Rel and ATF-1/CREB2.

21 January 2018

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Requirements for interleukin 2 promoter transactivation by the Tax protein of human T-cell leukemia virus type 1.

21 January 2018

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Regulation of T-cell lymphokine gene transcription by the accessory molecule CD28

21 January 2018

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CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines

21 January 2018

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The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65.

21 January 2018

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Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappaB/Rel transcription factors

21 January 2018

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Effect of CD28 signal transduction on c-Rel in human peripheral blood T cells

21 January 2018

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Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.

21 January 2018

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Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

21 January 2018

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Both CD28 ligands CD80 (B7-1) and CD86 (B7-2) activate phosphatidylinositol 3-kinase, and wortmannin reveals heterogeneity in the regulation of T cell IL-2 secretion.

21 January 2018

1 reference

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Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

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Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo

21 January 2018

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CD28 and T cell antigen receptor signal transduction coordinately regulate interleukin 2 gene expression in response to superantigen stimulation

21 January 2018

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Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta

21 January 2018

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Selective modulation of protein kinase C-theta during T-cell activation

21 January 2018

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Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death

21 January 2018

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Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

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Mice transgenic for a soluble form of murine CTLA-4 show enhanced expansion of antigen-specific CD4+ T cells and defective antibody production in vivo

21 January 2018

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Kinase phosphorylation: Keeping it all in the family

21 January 2018

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Involvement of Jun and Rel proteins in up-regulation of interleukin-4 gene activity by the T cell accessory molecule CD28.

21 January 2018

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AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

21 January 2018

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Multiple pathways control protein kinase C phosphorylation

21 January 2018

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Extracellular HIV-1 Tat protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells

21 January 2018

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CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation

21 January 2018

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PI 3-kinase: a pivotal pathway in T-cell activation?

21 January 2018

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Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

21 January 2018

1 reference

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Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

21 January 2018

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The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases

21 January 2018

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Mitogen-activated kinase kinase kinase 1 regulates T cell receptor- and CD28-mediated signaling events which lead to NF-kappaB activation.

21 January 2018

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The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines.

21 January 2018

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A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor

21 January 2018

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Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis

21 January 2018

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The roles of CD28 and CD40 ligand in T cell activation and tolerance

21 January 2018

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7 January 2021

CD28-deficient mice generate an impaired Th2 response to Schistosoma mansoni infection

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7 January 2021

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

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7 January 2021

T lymphocyte costimulation mediated by reorganization of membrane microdomains

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7 January 2021

Evidence for a role of CD28RE as a response element for distinct mitogenic T cell activation signals

1 reference

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7 January 2021

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression

1 reference

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7 January 2021

Phosphoinositide 3-kinase regulation of T cell receptor-mediated interleukin-2 gene expression in normal T cells

1 reference

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7 January 2021

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://api.crossref.org/works/10.1038%2F83144

7 January 2021

Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C

1 reference

https://api.crossref.org/works/10.1038%2F83144

7 January 2021

CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1038%2F83144

7 January 2021

Immune Hyperactivation of HIV-1-Infected T Cells Mediated by Tat and the CD28 Pathway

1 reference

https://api.crossref.org/works/10.1038%2F83144

7 January 2021

A negative role for phosphoinositide 3-kinase in T-cell antigen receptor function

1 reference

https://api.crossref.org/works/10.1038%2F83144

7 January 2021

Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin

1 reference

https://api.crossref.org/works/10.1038%2F83144

7 January 2021

Tpl-2 induces IL-2 expression in T-cell lines by triggering multiple signaling pathways that activate NFAT and NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2F83144

7 January 2021

Identifiers

DOI

10.1038/83144

1 reference

Dimensions Publication ID

3 July 2017

1031575838

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1 reference