TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway (Q28505835)

24 January 2017

title

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway (English)

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24 January 2017

9

Shizuo Akira

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author name string

Masahiro Yamamoto

1

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24 January 2017

Shintaro Sato

2

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24 January 2017

Hiroaki Hemmi

3

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24 January 2017

Satoshi Uematsu

4

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24 January 2017

Katsuaki Hoshino

5

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24 January 2017

Tsuneyasu Kaisho

6

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24 January 2017

Osamu Takeuchi

7

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24 January 2017

Kiyoshi Takeda

8

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24 January 2017

language of work or name

English

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publication date

1 November 2003

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24 January 2017

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24 January 2017

volume

4

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24 January 2017

issue

11

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24 January 2017

page(s)

1144–1150

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https://api.crossref.org/works/10.1038%2FNI986

24 January 2017

1 reference

Innate immune recognition

21 January 2018

1 reference

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Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

21 January 2018

1 reference

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Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice

21 January 2018

1 reference

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Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

21 January 2018

1 reference

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

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The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

Discrimination of bacterial lipoproteins by Toll-like receptor 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

21 January 2018

1 reference

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

21 January 2018

1 reference

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TIRAP: an adapter molecule in the Toll signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

Triggering the interferon antiviral response through an IKK-related pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

The Toll-IL-1 receptor adaptor family grows to five members.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

IRF3 mediates a TLR3/TLR4-specific antiviral gene program

21 January 2018

1 reference

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Essential role of IRF-3 in lipopolysaccharide-induced interferon-beta gene expression and endotoxin shock

21 January 2018

1 reference

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Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6.

21 January 2018

1 reference

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Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal

21 January 2018

1 reference

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Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex

21 January 2018

1 reference

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Cutting edge: mouse pellino-2 modulates IL-1 and lipopolysaccharide signaling

21 January 2018

1 reference

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Pellino2 activates the mitogen activated protein kinase pathway

21 January 2018

1 reference

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Pellino3, a novel member of the Pellino protein family, promotes activation of c-Jun and Elk-1 and may act as a scaffolding protein

21 January 2018

1 reference

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Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction

21 January 2018

1 reference

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A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways

21 January 2018

1 reference

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Unresponsiveness of MyD88-deficient mice to endotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI986

7 January 2021

Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes

1 reference

https://api.crossref.org/works/10.1038%2FNI986

7 January 2021

Endotoxin-induced maturation of MyD88-deficient dendritic cells

1 reference

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7 January 2021

Recognition of CpG DNA is mediated by signaling pathways dependent on the adaptor protein MyD88

1 reference

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7 January 2021

Adjuvant activities of immune response modifier R-848: comparison with CpG ODN

1 reference

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7 January 2021