A novel function for FOXP3 in humans: intrinsic regulation of conventional T cells (Q24304263)

negative regulation of T-helper 17 cell differentiation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Elia Stupka

12

0 references

Alicia N McMurchy

Alicia N McMurchy

1

0 references

Dejan Lazarevic

Dejan Lazarevic

7

0 references

Ignazio Stefano Piras

Ignazio S Piras

9

0 references

Davide Cittaro

Davide Cittaro

6

0 references

Megan K. Levings

Megan K Levings

14

0 references

Maria Grazia Roncarolo

Maria Grazia Roncarolo

11

0 references

author name string

Jana Gillies

2

0 references

Maria Concetta Gizzi

3

0 references

Michela Riba

4

0 references

Jose Manuel Garcia-Manteiga

5

0 references

Sara Di Nunzio

8

0 references

Alessandro Bulfone

10

0 references

Rosa Bacchetta

Preferential recruitment of interferon-gamma-expressing TH17 cells in multiple sclerosis.

13

0 references

language of work or name

English

0 references

publication date

21 February 2013

0 references

published in

Blood

0 references

volume

121

0 references

issue

8

0 references

page(s)

1265-75

0 references

cites work

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

The role of retinoic acid-related orphan receptor variant 2 and IL-17 in the development and function of human CD4+ T cells.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Human tumor-infiltrating Th17 cells have the capacity to differentiate into IFN-γ+ and FOXP3+ T cells with potent suppressive function.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Molecular Regulation ofCellular Immunity by FOXP3

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Romance of the three kingdoms: RORgammat allies with HIF1alpha against FoxP3 in regulating T cell metabolism and differentiation

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Transient regulatory T-cells: a state attained by all activated human T-cells.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Rarity of Human T Helper 17 Cells Is due to Retinoic Acid Orphan Receptor-Dependent Mechanisms that Limit Their Expansion

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Clinical and molecular profile of a new series of patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome: inconsistent correlation between forkhead box protein 3 expression and disease severity.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Point mutants of forkhead box P3 that cause immune dysregulation, polyendocrinopathy, enteropathy, X-linked have diverse abilities to reprogram T cells into regulatory T cells

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

FoxP3 interacts with linker histone H1.5 to modulate gene expression and program Treg cell activity

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Regulated and multiple miRNA and siRNA delivery into primary cells by a lentiviral platform

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Generation of potent and stable human CD4+ T regulatory cells by activation-independent expression of FOXP3.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Identification of IL-17-producing FOXP3+ regulatory T cells in humans.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Phenotypic and functional features of human Th17 cells

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Exploration, normalization, and genotype calls of high-density oligonucleotide SNP array data

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Regulatory T cells: mechanisms of differentiation and function

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Defective regulatory and effector T cell functions in patients with FOXP3 mutations.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

IL-17-producing human peripheral regulatory T cells retain suppressive function

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

ATG-induced expression of FOXP3 in human CD4(+) T cells in vitro is associated with T-cell activation and not the induction of FOXP3(+) T regulatory cells.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Wild-type FOXP3 is selectively active in CD4+CD25(hi) regulatory T cells of healthy female carriers of different FOXP3 mutations

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Helios expression is a marker of T cell activation and proliferation.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

Inflammatory effects of ex vivo human Th17 cells are suppressed by regulatory T cells.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021

IL-17+ regulatory T cells in the microenvironments of chronic inflammation and cancer.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2012-05-431023

7 January 2021