Transient receptor potential cation channel, subfamily V, member 4 (Q15324125)

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mammalian protein found in Mus musculus
  • OTRPC4
  • trpv4 channel
  • transient receptor potential protein 12
  • Trpv4
  • vanilloid receptor-like channel 2
  • vanilloid receptor-like protein 2
  • osmosensitive transient receptor potential channel 4
  • VR-OAC
  • TRP12
  • vanilloid receptor-related osmotically-activated channel
  • transient receptor potential cation channel subfamily V member 4
  • osm-9-like TRP channel 4
edit
Language Label Description Also known as
English
Transient receptor potential cation channel, subfamily V, member 4
mammalian protein found in Mus musculus
  • OTRPC4
  • trpv4 channel
  • transient receptor potential protein 12
  • Trpv4
  • vanilloid receptor-like channel 2
  • vanilloid receptor-like protein 2
  • osmosensitive transient receptor potential channel 4
  • VR-OAC
  • TRP12
  • vanilloid receptor-related osmotically-activated channel
  • transient receptor potential cation channel subfamily V member 4
  • osm-9-like TRP channel 4

Statements

molecular function
protein binding
determination method or standard
IPI
5 references
retrieved
14 February 2019
stated in
The TRPV4 channel contributes to intercellular junction formation in keratinocytes
GOA
curator
UniProt
UniProt protein ID
Q9EPK8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IPI
retrieved
14 February 2019
stated in
Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3
GOA
curator
UniProt
UniProt protein ID
Q9EPK8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IPI
retrieved
14 February 2019
stated in
The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IPI
retrieved
14 February 2019
stated in
An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IPI
retrieved
14 February 2019
stated in
Microfilament-associated Protein 7 Increases the Membrane Expression of Transient Receptor Potential Vanilloid 4 (TRPV4)
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IPI
calcium channel activity
determination method or standard
IDA
IEA
IMP
ISO
8 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPK8&geneProductId=UniProtKB:Q9EPK8
determination method or standard
ISO
retrieved
24 April 2018
stated in
TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis
GOA
curator
UniProt
UniProt protein ID
Q9EPK8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPK8&geneProductId=UniProtKB:Q9EPK8
determination method or standard
IMP
retrieved
24 April 2018
stated in
Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3
GOA
curator
UniProt
UniProt protein ID
Q9EPK8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPK8&geneProductId=UniProtKB:Q9EPK8
determination method or standard
IMP
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9EPK8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPK8&geneProductId=UniProtKB:Q9EPK8
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPK8&geneProductId=UniProtKB:Q9EPK8
determination method or standard
IEA
retrieved
24 April 2018
stated in
Microfilament-associated Protein 7 Increases the Membrane Expression of Transient Receptor Potential Vanilloid 4 (TRPV4)
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPK8&geneProductId=UniProtKB:Q9EPK8
determination method or standard
IDA
retrieved
24 April 2018
stated in
OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPK8&geneProductId=UniProtKB:Q9EPK8
determination method or standard
IDA
retrieved
24 April 2018
stated in
Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPK8&geneProductId=UniProtKB:Q9EPK8
determination method or standard
IDA
calcium channel activity
determination method or standard
IBA
IDA
IEA
IMP
ISO
9 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
ISO
retrieved
14 February 2019
stated in
TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis
GOA
curator
UniProt
UniProt protein ID
Q9EPK8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IMP
retrieved
14 February 2019
stated in
Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3
GOA
curator
UniProt
UniProt protein ID
Q9EPK8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IMP
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9EPK8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IEA
retrieved
14 February 2019
stated in
OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IDA
retrieved
14 February 2019
stated in
Microfilament-associated Protein 7 Increases the Membrane Expression of Transient Receptor Potential Vanilloid 4 (TRPV4)
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IDA
retrieved
14 February 2019
stated in
Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IBA
cell component
plasma membrane
determination method or standard
IDA
ISS
IEA
ISO
7 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9EPK8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9EPK8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IEA
retrieved
14 February 2019
stated in
The TRPV4 channel contributes to intercellular junction formation in keratinocytes
GOA
curator
UniProt
UniProt protein ID
Q9EPK8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IDA
retrieved
14 February 2019
stated in
Microfilament-associated Protein 7 Increases the Membrane Expression of Transient Receptor Potential Vanilloid 4 (TRPV4)
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IDA
retrieved
14 February 2019
stated in
Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPK8
determination method or standard
IDA
biological process

Identifiers

 
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