Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas (Q28207345)

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object named as

L Pasqualucci

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author name string

P Neumeister

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T Goossens

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G Nanjangud

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R S Chaganti

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R Dalla-Favera

Genetic instabilities in human cancers

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language of work or name

English

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publication date

19 July 2001

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published in

Nature

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volume

412

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issue

6844

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page(s)

341-6

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cites work

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Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

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Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

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DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

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BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

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Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

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Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction

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Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma

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Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma

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Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region

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Binding and suppression of the Myc transcriptional activation domain by p107.

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Nonrandom 4p13 rearrangements of the RhoH/TTF gene, encoding a GTP-binding protein, in non-Hodgkin's lymphoma and multiple myeloma

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Loss- and gain-of-function mutations reveal an important role of BSAP (Pax-5) at the start and end of B cell differentiation

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The TATA binding protein, c-Myc and survivin genes are not somatically hypermutated, while Ig and BCL6 genes are hypermutated in human memory B cells.

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Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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Progress in understanding the mechanism and consequences of somatic hypermutation

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Mutations in the first exon are associated with altered transcription of c-myc in Burkitt lymphoma

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Monitoring and interpreting the intrinsic features of somatic hypermutation

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Cytogenetic analysis of 363 consecutively ascertained diffuse large B-cell lymphomas

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