Antimetastatic potential of fisetin involves inactivation of the PI3K/Akt and JNK signaling pathways with downregulation of MMP-2/9 expressions in prostate cancer PC-3 cells (Q39820443)

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English	Antimetastatic potential of fisetin involves inactivation of the PI3K/Akt and JNK signaling pathways with downregulation of MMP-2/9 expressions in prostate cancer PC-3 cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Antimetastatic potential of fisetin involves inactivation of the PI3K/Akt and JNK signaling pathways with downregulation of MMP-2/9 expressions in prostate cancer PC-3 cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

prostate cancer

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Chi-Sheng Chien

1

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Kun-Hung Shen

2

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Jau-Shyang Huang

3

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Shian-Chin Ko

4

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Yuan-Wei Shih

5

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

publication date

26 July 2009

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Molecular and Cellular Biochemistry

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Europe PubMed Central

PubMed publication ID

14 September 2017

333

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Europe PubMed Central

PubMed publication ID

14 September 2017

1-2

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Europe PubMed Central

PubMed publication ID

14 September 2017

169-180

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Human mitogen-activated protein kinase kinase kinase mediates the stress-induced activation of mitogen-activated protein kinase cascades

1 reference

https://api.crossref.org/works/10.1007%2FS11010-009-0217-Z

21 January 2018

Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

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Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling pathways responsible for cancer cell invasion as targets for cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

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BKM1740, an acyl-tyrosine bisphosphonate amide derivative, inhibits the bone metastatic growth of human prostate cancer cells by inducing apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fisetin inhibits the activities of cyclin-dependent kinases leading to cell cycle arrest in HT-29 human colon cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Silibinin inhibits cell invasion through inactivation of both PI3K-Akt and MAPK signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

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Simvastatin inhibits TNFalpha-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Expression and significance of PTEN/PI3K signal transduction-related proteins in non-small cell lung cancer]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavonol-rich RVHxR from Rhus verniciflua Stokes and its major compound fisetin inhibits inflammation-related cytokines and angiogenic factor in rheumatoid arthritic fibroblast-like synovial cells and in vivo models

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of epigallocatechin-3-gallate inhibits matrix metalloproteinases-2 and -9 via inhibition of activation of mitogen-activated protein kinases, c-jun and NF-kappaB in human prostate carcinoma DU-145 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalph

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Ets-1 transcription factor is involved in the development and invasion of malignant melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

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Chemoinhibitory effect of mulberry anthocyanins on melanoma metastasis involved in the Ras/PI3K pathway

1 reference

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12 December 2020

based on heuristic

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Effects of flavonoids and vitamin C on oxidative DNA damage to human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary intakes of flavonols, flavones and isoflavones by Japanese women and the inverse correlation between quercetin intake and plasma LDL cholesterol concentration

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of matrix metalloproteinase expression in tumor invasion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fisetin, a flavonol, inhibits TH2-type cytokine production by activated human basophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-chaconine-reduced metastasis involves a PI3K/Akt signaling pathway with downregulation of NF-kappaB in human lung adenocarcinoma A549 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor (EGF)- and scatter factor/hepatocyte growth factor (SF/HGF)- mediated keratinocyte migration is coincident with induction of matrix metalloproteinase (MMP)-9.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carnosol inhibits the invasion of B16/F10 mouse melanoma cells by suppressing metalloproteinase-9 through down-regulating nuclear factor-kappa B and c-Jun

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally occurring anticarcinogenic substances in foodstuffs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer statistics, 2000.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19633975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of luteolin on hepatocyte growth factor/scatter factor-induced HepG2 cell invasion involving both MAPK/ERKs and PI3K-Akt pathways

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel dietary flavonoid fisetin inhibits androgen receptor signaling and tumor growth in athymic nude mice

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changing views of the role of matrix metalloproteinases in metastasis

1 reference

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12 December 2020

based on heuristic

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Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases

1 reference

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Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells

1 reference

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12 December 2020

based on heuristic

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Metastatic Inefficiency

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Prostate cancer in Taiwan: epidemiology and risk factors

1 reference

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Sustained ERK phosphorylation is necessary but not sufficient for MMP-9 regulation in endothelial cells: involvement of Ras-dependent and -independent pathways

1 reference

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12 December 2020

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Quercetin downregulates matrix metalloproteinases 2 and 9 proteins expression in prostate cancer cells (PC-3).

1 reference

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12 December 2020

based on heuristic

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Alpha-mangostin suppresses PC-3 human prostate carcinoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen expression through the JNK signaling pathway

1 reference

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Silibinin suppresses PMA-induced MMP-9 expression by blocking the AP-1 activation via MAPK signaling pathways in MCF-7 human breast carcinoma cells

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-009-0217-Z

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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