Activation of the Bcl-2 promoter by nerve growth factor is mediated by the p42/p44 MAPK cascade (Q39727977)

14 September 2017

Activation of the Bcl-2 promoter by nerve growth factor is mediated by the p42/p44 MAPK cascade (English)

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14 September 2017

Liu YZ

1

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14 September 2017

Boxer LM

series ordinal

2

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14 September 2017

Latchman DS

series ordinal

3

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14 September 2017

language of work or name

English

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publication date

1 May 1999

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14 September 2017

Nucleic Acids Research

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14 September 2017

27

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14 September 2017

10

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14 September 2017

2086-2090

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Bcl-2 and the regulation of programmed cell death

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The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis.

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Cell death during development of the nervous system

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Autocrine regulation of apoptosis and bcl-2 expression by nerve growth factor in early differentiating cerebellar granule neurons involves low affinity neurotrophin receptor.

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Pi 1 binding sites are negative regulators of bcl-2 expression in pre-B cells

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A negative regulatory element in the bcl-2 5'-untranslated region inhibits expression from an upstream promoter

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Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis

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Bcl-2 transcription from the proximal P2 promoter is activated in neuronal cells by the Brn-3a POU family transcription factor

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The N-terminal domain unique to the long form of the Brn-3a transcription factor is essential to protect neuronal cells from apoptosis and for the activation of Bbcl-2 gene expression

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Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB.

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The WT1 protein is a negative regulator of the normal bcl-2 allele in t(14;18) lymphomas

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Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

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Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

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Nerve growth factor stimulates the hydrolysis of glycosylphosphatidylinositol in PC-12 cells: a mechanism of protein kinase C regulation

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Cholinergic metabolism and synapse formation by a rat nerve cell line

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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Nerve growth factor rescues pigment cells from ultraviolet-induced apoptosis by upregulating BCL-2 levels

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The cyclic AMP response element in the calcitonin/calcitonin gene-related peptide gene promoter is necessary but not sufficient for its activation by nerve growth factor

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Nerve growth factor up-regulates the transcriptional activity of CBP through activation of the p42/p44(MAPK) cascade

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21 January 2018

Identifiers

DOI

10.1093/NAR/27.10.2086

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14 September 2017

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14 September 2017

PubMed publication ID

10219080

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