The polyphenol fisetin protects bone by repressing NF-κB and MKP-1-dependent signaling pathways in osteoclasts (Q34827459)

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5 March 2020

title

The polyphenol fisetin protects bone by repressing NF-κB and MKP-1-dependent signaling pathways in osteoclasts (English)

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5 March 2020

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5 March 2020

author name string

Laurent Léotoing

1

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5 March 2020

Fabien Wauquier

2

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5 March 2020

Elisabeth Miot-Noirault

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5 March 2020

Yohann Wittrant

5

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Véronique Coxam

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language of work or name

English

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publication date

4 July 2013

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5 March 2020

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volume

8

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issue

7

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5 March 2020

page(s)

e68388

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Creative Commons Attribution 4.0 International

5 March 2020

copyright license

start time

4 July 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Fisetin Inhibits Osteoclast Differentiation via Downregulation of p38 and c-Fos-NFATc1 Signaling Pathways

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ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease

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Antimetastatic potential of fisetin involves inactivation of the PI3K/Akt and JNK signaling pathways with downregulation of MMP-2/9 expressions in prostate cancer PC-3 cells

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A novel dietary flavonoid fisetin inhibits androgen receptor signaling and tumor growth in athymic nude mice

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Flavonol-rich RVHxR from Rhus verniciflua Stokes and its major compound fisetin inhibits inflammation-related cytokines and angiogenic factor in rheumatoid arthritic fibroblast-like synovial cells and in vivo models

21 January 2018

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Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-κB.

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Fisetin inhibits osteoclastogenesis through prevention of RANKL-induced ROS production by Nrf2-mediated up-regulation of phase II antioxidant enzymes.

21 January 2018

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Fisetin inhibits lipopolysaccharide-induced macrophage activation and dendritic cell maturation

21 January 2018

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26 October 2018

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c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling

21 January 2018

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Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalph

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23861901

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23861901

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0068388

1 reference

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5 March 2020

0 references

1 reference

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5 March 2020

PubMed publication ID

23861901

1 reference

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