A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres (Q33381789)

26 July 2017

title

A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres (English)

1 reference

26 July 2017

0 references

Sebastian Müller

2

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Raphaël Rodriguez

object named as

Raphaël Rodriguez

1

0 references

Jean-François Riou

object named as

Jean-François Riou

5

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Shankar Balasubramanian

6

object named as

Shankar Balasubramanian

1 reference

26 July 2017

Justin A Yeoman

3

1 reference

26 July 2017

Chantal Trentesaux

4

1 reference

26 July 2017

language of work or name

English

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publication date

1 November 2008

1 reference

Journal of the American Chemical Society

26 July 2017

published in

1 reference

26 July 2017

volume

130

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26 July 2017

issue

47

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26 July 2017

page(s)

15758-15759

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How shelterin protects mammalian telomeres

26 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

Living on a break: cellular senescence as a DNA-damage response

21 June 2018

1 reference

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Triarylpyridines: a versatile small molecule scaffold for G-quadruplex recognition

21 June 2018

1 reference

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Exploring the differential recognition of DNA G-quadruplex targets by small molecules using dynamic combinatorial chemistry.

21 June 2018

1 reference

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A hitchhiker's guide to G-quadruplex ligands

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action

21 June 2018

1 reference

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Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

The POT1-TPP1 telomere complex is a telomerase processivity factor

21 June 2018

1 reference

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Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells.

21 June 2018

1 reference

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Oxazole-based peptide macrocycles: a new class of G-quadruplex binding ligands

21 June 2018

1 reference

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The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells

21 June 2018

1 reference

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Shelterin: the protein complex that shapes and safeguards human telomeres

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

Preferential binding of a G-quadruplex ligand to human chromosome ends.

21 June 2018

1 reference

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Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins

21 June 2018

1 reference

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Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

21 June 2018

1 reference

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A DNA damage checkpoint response in telomere-initiated senescence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

Fluorescence resonance energy transfer as a probe for G-quartet formation by a telomeric repeat

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

Switching and signaling at the telomere

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

Pot1, the putative telomere end-binding protein in fission yeast and humans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

Inhibition of telomerase by G-quartet DNA structures

21 June 2018

1 reference

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Selective recognition of a DNA G-quadruplex by an engineered antibody

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

A platinum supramolecular square as an effective G-quadruplex binder and telomerase inhibitor

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

Ligand-driven G-quadruplex conformational switching by using an unusual mode of interaction

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

Targeting telomeres and telomerase

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746963

Inhibition of human telomerase by a G-quadruplex-interactive compound

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18975896

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JA805615W

1 reference

26 July 2017

1 reference

26 July 2017

1 reference