A dominant negative Egr inhibitor blocks nerve growth factor-induced neurite outgrowth by suppressing c-Jun activation: role of an Egr/c-Jun complex (Q28569247)

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English	A dominant negative Egr inhibitor blocks nerve growth factor-induced neurite outgrowth by suppressing c-Jun activation: role of an Egr/c-Jun complex	scientific journal article

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scholarly article

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31 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12019303%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

A dominant negative Egr inhibitor blocks nerve growth factor-induced neurite outgrowth by suppressing c-Jun activation: role of an Egr/c-Jun complex (English)

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12019303%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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author name string

Yechiel Levkovitz

1

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PubMed publication ID

31 January 2017

Europe PubMed Central

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9 November 2019

Jay M Baraban

2

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Europe PubMed Central

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9 November 2019

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1 May 2002

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9 November 2019

Journal of Neuroscience

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12019303%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

22

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12019303%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

10

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12019303%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

3845-3854

1 reference

Europe PubMed Central

PMC publication ID

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9 November 2019

EGR2 mutations in inherited neuropathies dominant-negatively inhibit myelin gene expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor induces zif268 gene expression via MAPK-dependent and -independent pathways in PC12D cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the RelA(p65) NF-kappaB subunit by Egr-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular signaling pathways activated by neurotrophic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A requirement for the immediate early gene Zif268 in the expression of late LTP and long-term memories

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-regulation of the mitogen-activated protein kinase, extracellular signal-regulated kinase 1, and the 90-kDa ribosomal S6 kinase in PC12 cells. Distinct effects of the neurotrophic factor, nerve growth factor, and the mitogenic factor, epidermal g

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of transcription by MAP kinase cascades

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor, but not epidermal growth factor, increases Fra-2 expression and alters Fra-2/JunD binding to AP-1 and CREB binding elements in pheochromocytoma (PC12) cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An enhanced expression of the immediate early gene, Egr-1, is associated with neuronal apoptosis in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Base sequence discrimination by zinc-finger DNA-binding domains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding studies with mutants of Zif268. Contribution of individual side chains to binding affinity and specificity in the Zif268 zinc finger-DNA complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early responses of PC-12 cells to NGF and EGF: effect of K252a and 5'-methylthioadenosine on gene expression and membrane protein methylation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of EGR1 in hippocampal synaptic enhancement induced by tetanic stimulation and amputation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcriptional corepressor NAB2 inhibits NGF-induced differentiation of PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The early response gene NGFI-C encodes a zinc finger transcriptional activator and is a member of the GCGGGGGCG (GSG) element-binding protein family

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Krox-20 controls myelination in the peripheral nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen blocks M-CSF gene expression and osteoclast formation by regulating phosphorylation of Egr-1 and its interaction with Sp-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor ATF2 regulation by the JNK signal transduction pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of NGF-induced neurite outgrowth by a dominant-negative inhibitor of the egr family of transcription regulatory factors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of an immediate early gene egr-1 by zinc through extracellular signal-regulated kinase activation in cortical culture: its role in zinc-induced neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA binding site of the growth factor-inducible protein Zif268

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA-binding specificity of NGFI-A and related zinc finger transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase cascades activated by stress and inflammatory cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p38 mitogen-activated protein kinase regulates low potassium-induced c-Jun phosphorylation and apoptosis in cultured cerebellar granule neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intramolecular signal transduction in c-Jun

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The EGR family of transcription-regulatory factors: progress at the interface of molecular and systems neuroscience.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PC12h-R cell, a subclone of PC12 cells, shows EGF-induced neuronal differentiation and sustained signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor- and epidermal growth factor-regulated gene transcription in PC12 pheochromocytoma and INS-1 insulinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of c-jun mediated by MAP kinases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium controls gene expression via three distinct pathways that can function independently of the Ras/mitogen-activated protein kinases (ERKs) signaling cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nuclear localization signal of NGFI-A is located within the zinc finger DNA binding domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dominant negative inhibitor of the Egr family of transcription regulatory factors suppresses cerebellar granule cell apoptosis by blocking c-Jun activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional comparison of Egr3 transcription factor isoforms: identification of an activation domain in the N-terminal segment absent from Egr3beta, a major isoform expressed in brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12019303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.22-10-03845.2002

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12019303%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12019303%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12019303%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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