hydroxymethylglutaryl-CoA synthase activity (Q21118282)

Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+).

(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)
hydroxymethylglutaryl coenzyme A synthase activity
(s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity
3-hydroxy-3-methylglutaryl-coenzyme A synthase activity
3-hydroxy-3-methylglutaryl CoA synthetase activity
acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
beta-hydroxy-beta-methylglutaryl-CoA synthase activity
acetoacetyl coenzyme A transacetase activity
hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity
3-hydroxy-3-methylglutaryl coenzyme A synthase activity
HMG-CoA synthase activity
3-hydroxy-3-methylglutaryl coenzyme A synthetase activity
GO:0004421
3-hydroxy-3-methylglutaryl-CoA synthase activity

Language	Label	Description	Also known as
English	hydroxymethylglutaryl-CoA synthase activity	Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+).	(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating) hydroxymethylglutaryl coenzyme A synthase activity (s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity 3-hydroxy-3-methylglutaryl-coenzyme A synthase activity 3-hydroxy-3-methylglutaryl CoA synthetase activity acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming) beta-hydroxy-beta-methylglutaryl-CoA synthase activity acetoacetyl coenzyme A transacetase activity hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity 3-hydroxy-3-methylglutaryl coenzyme A synthase activity HMG-CoA synthase activity 3-hydroxy-3-methylglutaryl coenzyme A synthetase activity GO:0004421 3-hydroxy-3-methylglutaryl-CoA synthase activity