PPARG coactivator 1 alpha (Q21118081)

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mammalian protein found in Homo sapiens
  • PPARGC1A
  • ligand effect modulator-6
  • L-PGC-1alpha
  • PGC-1-alpha
  • peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a
  • peroxisome proliferator-activated receptor gamma coactivator 1-alpha
  • PPARGC-1-alpha
  • Ligand effect modulator 6
  • PPAR gamma coactivator variant form
  • peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext
  • PPARgamma coactivator 1alpha
  • peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT
edit
Language Label Description Also known as
English
PPARG coactivator 1 alpha
mammalian protein found in Homo sapiens
  • PPARGC1A
  • ligand effect modulator-6
  • L-PGC-1alpha
  • PGC-1-alpha
  • peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a
  • peroxisome proliferator-activated receptor gamma coactivator 1-alpha
  • PPARGC-1-alpha
  • Ligand effect modulator 6
  • PPAR gamma coactivator variant form
  • peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext
  • PPARgamma coactivator 1alpha
  • peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT

Statements

molecular function
protein binding
determination method or standard
IPI
8 references
retrieved
8 April 2019
stated in
Structural activity relationship of flavonoids with estrogen-related receptor gamma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
IPI
retrieved
8 April 2019
stated in
Phosphorylation-dependent sumoylation regulates estrogen-related receptor-alpha and -gamma transcriptional activity through a synergy control motif
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
IPI
retrieved
8 April 2019
stated in
Evidence for ligand-independent transcriptional activation of the human estrogen-related receptor alpha (ERRalpha): crystal structure of ERRalpha ligand binding domain in complex with peroxisome proliferator-activated receptor coactivator-1alpha
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
IPI
retrieved
8 April 2019
stated in
Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
IPI
retrieved
8 April 2019
stated in
Kaempferol is an estrogen-related receptor alpha and gamma inverse agonist
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
IPI
retrieved
8 April 2019
stated in
Multiple binding modes between HNF4alpha and the LXXLL motifs of PGC-1alpha lead to full activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
IPI
retrieved
8 April 2019
stated in
Communication between the ERRalpha homodimer interface and the PGC-1alpha binding surface via the helix 8-9 loop
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
IPI
retrieved
8 April 2019
stated in
The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
IPI
cell component
nucleus
determination method or standard
IDA
ISS
TAS
IEA
5 references
retrieved
5 June 2018
stated in
Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator
GOA
curator
UniProt
UniProt protein ID
Q9UBK2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UBK2&geneProductId=UniProtKB:Q9UBK2
determination method or standard
TAS
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UBK2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UBK2&geneProductId=UniProtKB:Q9UBK2
determination method or standard
ISS
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UBK2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UBK2&geneProductId=UniProtKB:Q9UBK2
determination method or standard
IEA
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UBK2&geneProductId=UniProtKB:Q9UBK2
determination method or standard
IEA
retrieved
5 June 2018
stated in
Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells
GOA
curator
UniProt
UniProt protein ID
Q9UBK2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UBK2&geneProductId=UniProtKB:Q9UBK2
determination method or standard
IDA
nucleus
determination method or standard
IBA
IDA
IEA
ISS
TAS
6 references
retrieved
8 April 2019
stated in
Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator
GOA
curator
UniProt
UniProt protein ID
Q9UBK2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UBK2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UBK2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
IEA
retrieved
8 April 2019
stated in
Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells
GOA
curator
UniProt
UniProt protein ID
Q9UBK2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBK2
determination method or standard
IBA
biological process

Identifiers

Freebase ID
/m/03cs9y3
0 references
Microsoft Academic ID
12304452
0 references
2909414174
0 references
 
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