trisomy 21


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Related to trisomy 21: trisomy 21 syndrome

trisomy 21

n.
See Down syndrome.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

Down′

(or Down's′) syn′drome


n.
a genetic disorder associated with the presence of an extra chromosome 21, characterized by mental retardation, weak muscle tone, and epicanthic folds at the eyelids.
Formerly, mongolism. Also called trisomy 21.
[1960–65; after John Latin. H. Down (1828–96), British physician]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.trisomy 21 - a congenital disorder caused by having an extra 21st chromosometrisomy 21 - a congenital disorder caused by having an extra 21st chromosome; results in a flat face and short stature and mental retardation
Down syndrome, Down's syndrome, mongolianism, mongolism
birth defect, congenital abnormality, congenital anomaly, congenital defect, congenital disorder - a defect that is present at birth
trisomy - chrosomal abnormality in which there is one more than the normal number of chromosomes in a cell
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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"Advanced maternal age is a well-recognised factor that increases a woman's risk of having a child with chromosomal abnormalities, such as Trisomy 21. Trisomy 21, commonly known as Down syndrome, occurs due to the presence of an extra copy of chromosome 21," said Mulla.
'Advanced maternal age increases risk of Down Syndrome in babies'
He said there was also a need to run an awareness campaign for educating the people about trisomy 21.
Children suffering from Down Syndrome, govt's responsibility: CM
In a message issued here on Wednesday, the Chief said that there is also a need to run an awareness campaign for educating the people about trisomy 21.
Buzdar for awareness campaign against children disease
According to the World Health Organization (WHO), Down Syndrome also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21.
WORLD DOWN SYNDROME DAY TODAY, VARIOUS ACTIVITIES PLANNED
The positive predictive value in this cohort was 95.2% for trisomy 21, 93.5% for trisomy 18, 77.9% for trisomy 13, and 86.7% for monosomy X.
Natera: Study shows high predictive values in determining genetic abnormalities
It is well established that trisomy 21 pregnancies are associated with increased maternal age, increased fetal Nuchal Translucency (NT) thickness, increased maternal serum free Beta Human Chorionic Gonadotropin (free BHCG) and decreased maternal serum Pregnancy Associated Plasma Protein- A (PAPP-A) (3).
Triploidy and Routine Combined First Trimester Pregnancy Screening
Down syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21.
Geneticist claims to have solved Down Syndrome
Now, the link between Down syndrome and Alzheimer's is being studied further, with new research recently shared by the Trisomy 21 Research Society.
New Hope for Those Living with Alzheimer's disease?
Professional guidelines recommend cfDNA testing for trisomy 21, 18, and 13 for pregnant women at high risk for fetal aneuploidy; some guidelines support testing for all women.
Review Addresses Cell-Free DNA Sequencing in Pregnancy; cfDNA testing for trisomy 21, 18, 13 recommended in pregnancy; no FDA oversight for testing
Trisomy 21 is also a risk factor for a number of diseases, such as congenital heart disease, which is the most common disease that occurs in 40%-50% of patients with DS (2).
MicroRNA Expression Profile in the Prenatal Amniotic Fluid Samples of Pregnant Women with Down Syndrome
Trisomy 21 is the main cause of Down syndrome (DS) and it is associated with various other clinical phenotypes such as Alzheimer's disease, congenital heart diseases, cancers, Hirschsprung's disease, leukemias, epilepsy, sleep disorder, infertility-related issues, and a various nutrient deficiencies.
Segmental duplication-quantitative fluorescent-polymerase chain reaction: An approach for the diagnosis of Down syndrome in India/Segmental duplikasyon-kantitatif floresan polimeraz zincir reaksiyonu: Hindistan'da Down sendromu tanisina yonelik bir yaklasim

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