Submandibular gland is almond-shaped in rats and is separated from ligaments by a thin membrane (Sbarbati et al., 1994).
In rats, major salivary gland is the
submandibular gland (SMG), and it is considered as an excellent model to study pre- and post-natal development of salivary glands (Wang et al., 2014).
Of the 12 sialolithiasis patients, eight had
submandibular gland stones, and four had parotid gland stones (Table 2).
Intraoperatively a smooth, spongy, mass with a feeding artery at the base is seen in the region of
submandibular gland replacing it, feeding artery was ligated and cut and the swelling is excised in full (Fig.
Finally we evaluated the nasal septum and
submandibular gland histopathologically.
In addition, it has been reported that genetically induced obesity (Zucker rats) promotes proinflammatory changes in the
submandibular gland, and is also associated with rampant caries, despite there being no alterations in the architecture of the glandular tissue (25).
Human submandibular salivary gland lies inferior to mylohyoid muscle while rat
submandibular gland lies on anterior side of neck having submandibular lymph nodes on one side and sternum on the other side.
However, depending on the location of sialolith (e.g., mainly in the duct of the
submandibular gland), occlusal radiograph can be used for its visualisation [3, 8] if it is located in the glandular parenchyma; otherwise, other imaging examinations allow a better visualisation.
Computed tomography (CT) scan neck region revealed a well-defined 3.0 x 2.2 x 2.0 cm uniloculated lesion located anteroinferior to the right
submandibular gland with imperceptible wall.
In both the 2nd and 4th weeks of the experiment, the number of vacuoles was higher in the parotid gland as compared to the
submandibular gland (Figure 5, Table 3).
A horizontal skin incision was made in the upper part of the neck, and the
submandibular gland was removed to ensure a wide surgical field (Figure 3).
On physical exam, he was found to have bilateral parotid and
submandibular gland enlargement and right eye proptosis.