repressor

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re·pres·sor

 (rĭ-prĕs′ər)
n.
1. also re·press·er One that represses.
2. Genetics A protein that binds to an operator, blocking transcription of an operon and the enzymes for which the operon codes.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

repressor

(rɪˈprɛsə)
n
(Genetics) biochem a protein synthesized under the control of a repressor gene, which has the capacity to bind to the operator gene and thereby shut off the expression of the structural genes of an operon
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

re•pres•sor

(rɪˈprɛs ər)

n.
a protein that binds DNA at an operator site and thereby prevents transcription of one or more adjacent genes.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.repressor - an agent that represses
represser
agent - an active and efficient cause; capable of producing a certain effect; "their research uncovered new disease agents"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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References in periodicals archive ?
Caption: FIGURE 2: PPAR[gamma] mediated transrepression of NF-[kappa]B through SUMOylation modification.
Signaling Mechanisms of Selective PPAR[gamma] Modulators in Alzheimer's Disease
EPZ005687 treatment was used to validate the role of EZH2 in SOD1 transrepression. Indeed, EPZ005687 treatment could reverse the increased accumulation of EZH2 and H3K27Me3 on SOD1 promoter (Figure 4(c)) and increase SOD1 expression in lung in TAC-induced PAH mice (Figures 4(a) and 4(b)).
EZH2 Inhibition Ameliorates Transverse Aortic Constriction-Induced Pulmonary Arterial Hypertension in Mice
The first NR4A1 agonist, 6-mercaptopurine, is obtained through high-throughput screening, and it inhibits tumor necrosis factor-[alpha] production in microglia via NR4A1-mediated transrepression and PI3K/ Akt/mTOR signaling-mediated posttranslational modification.
The Orphan Nuclear Receptor 4A1: A Potential New Therapeutic Target for Metabolic Diseases
The nuclear receptor Rev-ERB[alpha], which represses the transcription of Bmal1, contains negative GREs mediating GR transrepression [35].
Perinatal Programming of Circadian Clock-Stress Crosstalk
Baldwin Jr, "Characterization of mechanisms involved in transrepression of NF-[kappa]B by activated glucocorticoid receptors," Molecular and Cellular Biology, vol.
CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms
An ADIOL-ER[beta]-CtBP transrepression pathway negatively regulates microgliamediated inflammation.
Differential activation of a mouse estrogen receptor [beta] isoform (mER[beta]2) with endocrine-disrupting chemicals (EDCS)
Saijo, "Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells," Nature Reviews Immunology, vol.
Targeting Peroxisome Proliferator-Activated Receptors Using Thiazolidinediones: Strategy for Design of Novel Antidiabetic Drugs
• Retains anti-inflammatory (transrepression) activity.
Ryan's Quest Clinical Trial Grant for Steroid Alternative
Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPAR[gamma].
Correlation between E3 SUMO-Protein Ligase NSE2 (NSMCE2) with 5'-nucleotidase, XOR, uric acid and total protein in patients with atherosclerosis
Glass, "PPARs and molecular mechanisms of transrepression," Biochimica et Biophysica Acta, vol.
PPAR[gamma] networks in cell signaling: update and impact of cyclic phosphatidic acid

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