This document discusses serial communication between an Arduino and MATLAB. It explains that serial communication involves transferring data one bit at a time. A buffer is used to store data as it is sent and received asynchronously. The document provides examples of setting up a serial port object in MATLAB, configuring communication settings like baud rate, and using functions like fwrite and fscanf to send data from and receive data into MATLAB. It also briefly discusses reading from and writing to the serial port in Arduino code.