The document discusses different ways to create graphical user interfaces (GUIs) in MATLAB. It describes GUIDE, the MATLAB GUI development environment, which provides tools to simplify laying out and programming GUIs. It also discusses programmatically creating GUIs by writing code files that generate GUI functions or scripts. An example is provided of programmatically generating a simple GUI with push buttons, a pop-up menu, static text, and an axes component to display plots.