Session 31 - Identification of Patients With Syphilis
The document outlines a training session on the identification, causes, transmission, symptoms, treatment, and prevention of syphilis, a chronic disease caused by the bacterium Treponema pallidum. It details the stages of syphilis, including primary, secondary, and tertiary manifestations, as well as recommended treatments and preventive measures such as abstinence and condom use. The session includes activities for student engagement and evaluation to reinforce learning outcomes.
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Session 31 - Identification of Patients With Syphilis
The document outlines a training session on the identification, causes, transmission, symptoms, treatment, and prevention of syphilis, a chronic disease caused by the bacterium Treponema pallidum. It details the stages of syphilis, including primary, secondary, and tertiary manifestations, as well as recommended treatments and preventive measures such as abstinence and condom use. The session includes activities for student engagement and evaluation to reinforce learning outcomes.
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Disease Control and Prevention
PST 04102: Identification of
Patients with Syphilis
Session 31: 120 minutes + Assignment 2 hours
Learning Tasks By the end of this session students are expected to be able to: • Describe Causes of Syphilis • Describe Mode of Transmission of Syphilis • Describe Major Signs and Symptoms of Syphilis • Explain Treatment of Syphilis • Explain Prevention and Control of Syphilis Causes of Syphilis • Syphilis: A chronic multi-systemic disease caused by the bacteria spirochetal bacterium Treponema pallidum. Mode of Transmission of Syphilis • The spirochaete Treponema pallidum enters the body through mucous membranes and skin. • The route of transmission of syphilis is almost always through sexual contact, although there are other routes such as: o Congenital Syphilis via transmission from mother to child in utero. o Transfusion of unscreened blood. o A patient with secondary syphilis who has mucosal or cutaneous lesion may transmit the disease through physical contact. o Unusual but possible transmission is accidental contact with infective tissue. Activity: Buzzing (5 minutes) • What are the signs and symptoms of syphilis? Signs and Symptoms of Syphilis There are 3 main stages of the disease namely: • Primary Syphilis • Secondary Syphilis • Tertiary Syphilis
Note: Different manifestations occur depending on the stage of
the disease; as outlined below: Primary Syphilis • Primary syphilis is typically acquired via direct sexual contact with the infectious lesions of a person with syphilis. • Approximately 10-90 days after the initial exposure (average 21 days), a skin lesion appears at the point of contact, which is usually the genitalia, but can be anywhere on the body oThis lesion, called a chancre which is a firm, painless skin ulceration localized at the point of initial exposure to the spirochete, often on the penis, vagina, rectum or elsewhere like lips, tongue, breast etc. • The lesion may persist for 4 to 6 weeks and usually heals spontaneously. • Local lymph node swelling can occur. Secondary Syphilis • Secondary syphilis occurs approximately 1–6 months (commonly 6 to 8 weeks) after the primary infection. • There are many different manifestations of secondary disease. • A patient with syphilis is most contagious when he or she has secondary syphilis. • There may be a symmetrical reddish pink non-itchy rash on the trunk and extremities • This is accompanied with mild constitutional systems, often described as flu-like. • These rashes tend to be symmetrical can involve the palms of the hands and the soles of the feet. • In moist areas of the body such as anus, vulva, perineum, mouth, and axilla the rash becomes flat, broad, whitish lesions known as condylomata lata. • All of these lesions are infectious and harbor active treponema organisms Tertiary Syphilis • Tertiary syphilis usually occurs 1–10 years after the initial infection, though in some • Cases it can take up to 50 years. • This stage is characterized by the formation of gummas which are soft, tumor-like lesions of inflammation known as granulomas. • They may appear almost anywhere in the body including the skeleton and brain. • The more severe manifestations include neurosyphilis and cardiovascular syphilis • The incubation period of syphilis varies from 10 days to 10 weeks with average of 3 weeks. Activity: Brainstorming (5 minutes) • Which drugs are used in the treatment of syphilis? Treatment of Syphilis • The drug of choice is intramuscular Benzathine benzylpenicillin • Doxycycline • Erythromycin Prevention and Control of Syphilis • Abstinence o Encourage delaying sexual activity for young people • Sexual and reproductive health education to young people in and out of school • Faithfulness (have one faithful uninfected partner) • Using condoms correctly and consistently o myths and misconceptions about condoms • Screening and effective treatment of asymptomatic cases • Effective treatment of STIs/RTIs • Voluntary counseling and testing (VCT) • Screening of blood for transfusion • All pregnant women should be screened for syphilis routinely to prevent congenital syphilis Key Points • Syphilis is sexually transmitted diseases cause by Treponema pallidum • Syphilis is a disease characterized by a primary lesion, a later secondary eruption and tertiary manifestation. • Syphilis can also be transmitted from mother to the newborn leading to congenital Syphilis. • Syphilis can be prevented by proper and consistent condom use. Evaluation • What causes Syphilis? • What is the mode of transmission of Syphilis? • What are the signs and symptoms of Syphilis? • What is the treatment of Syphilis? • What are preventive and control measure of Syphilis? Activity: Take Home Assignment (5 minutes) • DIVIDE students in groups or individuals • ASK the students to work on the following Assignment • Prepare a presentation to be delivered to the class indicating prevention and control methods of Syphilis.
• ALLOCATE time for students to do the assignments and submit
• REFER students to recommended reference References: • Cook, G, & Zumla, A. (2003). Manson’s Tropical Diseases. (21st ed.). London: Saunders Ltd. • Denyer, S. P. Hodges, N. A., & Gorman, S. P (2011) Ed. Hugo & Russell’s Pharmaceutical Microbiology (8th ed). Oxford: Willey-Blackwell publishing • Eshuis, J, & Manschot, P. (1992). Communicable diseases, (1st ed). Nairobi: AMREF • GoT (2004): National Infection Prevention and Control (IPC) Guidelines for Healthcare Workers. Dar es Salaam: MOHSW • GoT (2007) National Guidelines for Management of Sexually Transmitted and Reproductive Tract Infections (1sted). Dar es Salaam: MOHSW • GoT (2013) Standard Treatment Guidelines & National Essential Medicines List (4thed). Dar es Salaam: MOHSW • Nordberg, E., Kingondu, T., & Mugambi, E., et al. (2008) Communicable Diseases. (4thed.). Nairobi: AMREF. • Nordberg, E. (1999): Communicable Diseases, A Manual for Health Workers in Sub-Saharan Africa, Nairobi: AMREF