IBBiology2023NewSyllabus B1.1 Carbohydrates and Lipids PowerPoint-1
IBBiology2023NewSyllabus B1.1 Carbohydrates and Lipids PowerPoint-1
IBBiology2023NewSyllabus B1.1 Carbohydrates and Lipids PowerPoint-1
2023
B1.1
Carbohydrates
and Lipids
Sub-Topic Clarification
B1.1.1—Chemical properties of a carbon atom allowing for the formation Students should understand the nature of a covalent bond. Students should also understand that a carbon atom can form up to four single bonds or a combination of single
of diverse compounds upon which life is based and double bonds with other carbon atoms or atoms of other non-metallic elements. Include among the diversity of carbon compounds examples of molecules with branched
or unbranched chains and single or multiple rings. NOS: Students should understand that scientific conventions are based on international agreement (SI metric unit prefixes
“kilo”, “centi”, “milli”, “micro” and “nano”).
B1.1.2—Production of macromolecules by condensation reactions that Students should be familiar with examples of polysaccharides, polypeptides and nucleic acids.
link monomers to form a polymer
B1.1.3—Digestion of polymers into monomers by hydrolysis reactions Water molecules are split to provide the -H and -OH groups that are incorporated to produce monomers, hence the name of this type of reaction.
B1.1.4—Form and function of monosaccharides Students should be able to recognize pentoses and hexoses as monosaccharides from molecular diagrams showing them in the ring forms. Use glucose as an example of the
link between the properties of a monosaccharide and how it is used, emphasizing solubility, transportability, chemical stability and the yield of energy from oxidation as
properties.
B1.1.5—Polysaccharides as energy storage compounds Include the compact nature of starch in plants and glycogen in animals due to coiling and branching during polymerization, the relative insolubility of these compounds due to
large molecular size and the relative ease of adding or removing alpha-glucose monomers by condensation and hydrolysis to build or mobilize energy stores.
B1.1.6—Structure of cellulose related to its function as a structural Include the alternating orientation of beta-glucose monomers, giving straight chains that can be grouped in bundles and cross-linked with hydrogen bonds.
polysaccharide in plants
B1.1.8—Hydrophobic properties of lipids Lipids are substances in living organisms that dissolve in non-polar solvents but are only sparingly soluble in aqueous solvents. Lipids include fats, oils, waxes and steroids.
B1.1.9—Formation of triglycerides and phospholipids by condensation One glycerol molecule can link three fatty acid molecules or two fatty acid molecules and one phosphate group.
reactions
B1.1.10—Difference between saturated, monounsaturated and Include the number of double carbon (C=C) bonds and how this affects melting point. Relate this to the prevalence of different types of fatty acids in oils and fats used for
polyunsaturated fatty acids energy storage in plants and endotherms respectively.
B1.1.11—Triglycerides in adipose tissues for energy storage and thermal Students should understand that the properties of triglycerides make them suited to long-term energy storage functions. Students should be able to relate the use of
insulation triglycerides as thermal insulators to body temperature and habitat.
B1.1.12—Formation of phospholipid bilayers as a consequence of the Students should use and understand the term “amphipathic”.
hydrophobic and hydrophilic regions
B1.1.13—Ability of non-polar steroids to pass through the phospholipid Include oestradiol and testosterone as examples. Students should be able to identify compounds as steroids from molecular diagrams.
bilayer
Organic
Molecules
• In chemistry, organic
means “contains carbon”.
• Organic molecules are
those that are synthesized
by living organisms.
• They are all carbon-based
as a result of carbon’s
ability to form a diversity
of stable compounds.
of Carbon s
Properties of
Carbon
• Carbon has 4 valence electron, and therefore can form
up to 4 covalent bonds (tetrahedral).
• Long chains of carbon atoms are bonded together to
form a skeleton for organic molecules
• Different lengths
• Different arrangement (straight, branched,
ring)
• Different bond types (single, double, triple)
• Different bonds, rings, and functional groups may be
added on to the skeleton to change the properties of
the molecule.
Ethan Propan 1- 2-
e e Butene Butene
(b) (d) Presence of
Branching rings
Butan 2-
Cyclohexan Benzen
e Methylpropane
e e
© Created by Alyssa 2023
(isobutane)
B1.1.1—Chemical properties of a carbon atom allowing for the formation of diverse compounds upon which life is based
Hydrocarbons
• Hydrocarbons are molecules consisting of
only carbon and hydrogen
• Hydrocarbons are found in many of a
cell’s organic molecules
100 µm
(a) A fat molecule(b) Mammalian adipose cells
Isomers
H
CO2H CO2H
• Structural
• Geometric (c) EnantiomersC C
H
H NH2 NH2
Estradiol Testosterone
Functional Groups
Chemistry of Life:
Aldehyde
Acetone Propanal
• Hydroxyl
Carboxyl group (—COOH) Carboxylic acid
or organic acid
• Amino
• Sulfhydryl Sulfhydryl group (—SH) Thiol
Glycine
• Methyl Cysteine
• Phosphate
Phosphate group (—OPO 32−) Organic
phosphate
Glycerol
phosphate
compound 5-Methylcytosine
Metabolism
Chemical reactions of life:
• Forming bonds between molecules
• Dehydration synthesis
• Synthesis
• Anabolic reactions
• Breaking bonds between molecules
• Hydrolysis
• Digestion
• Catabolic reactions
© Created by Alyssa 2023
B1.1.2—Production of macromolecules by condensation reactions that link monomers to form a polymer
Types of
Metabolic
Reactions
Endergonic
The Synthesis of
Polymers
HO 1 2 3 4 H
Longer polymer
(a) Dehydration reaction in the synthesis of a polymer
Dehydration Synthesis
enzyme
H2 O
enzyme
Types of Metabolic
Reactions
Exergonic
• Breaking bonds
between
molecules
• Hydrolysis
• Release energy
• Digestion
• Catabolic reactions
The Breakdown
of Polymers
Polymers can disassemble by hydrolysis (addition of water
molecules).
HO 1 2 3 4 H
HO 1 2 3 H HO H
(b) Hydrolysis of a polymer
© Created by Alyssa 2023
B1.1.3—Digestion of polymers into monomers by hydrolysis reactions
Hydrolysis
enzyme
H2 O
enzyme
Endergoni
c vs. +G
Exergonic -G
Reactions
Condensation Hydrolysis
Energy Energy
consumed Released
Condensati
Covalent bond Covalent
on vs formed bond broken
Hydrolysis
Water removed Water Added
Monomer Polymer
Polymer Monomer
Monomer:
Monosaccharides
Simple Sugar
Molecules
• Composed of C,H,O
(CH2O)n
• Contains 3-7 carbons
• Name often ends in
–ose
• Short-term energy storage
Structure of Glucose
hexose (6-sided) sugar
Ribose
pentose (5-sided) sugar
Carbohydrat
es
O
H
C 6
CH2OH
1
6
CH2OH
2
CH2OH
H C OH 5C O H C
5
O 6
H H H O
3
H H 5 H
HO C H
H H
H
4
C OH C
1
C
4 1
C
4
OH 4
OH
1
H C OH H H
Structure of
O HO 3 2 OH
OH OH
3 C 2
C 3
C C
2 OH
H C
5
OH
H OH
H OH H OH
Carbohydrates
H 6
C OH
Examples of Monosaccharides
Triose sugars Pentose sugars Hexose sugars
(C3H6O3) (C5H10O5) (C6H12O6)
H O H O H O H O
C C C C
Aldoses H C OH H C OH H C OH H C OH
H C OH H C OH HO C H HO C H
H H C OH H C OH HO C H
H C OH H C OH H C OH
Glyceraldehyde
H H C OH H C OH
Ribose H H
Glucose Galactose
H H H
H C OH H C OH H C OH
C O C O C O
Ketoses
H C OH H C OH HO C H
H H C OH H C OH
Dihydroxyacetone H C OH H C OH
H H C OH
Ribulose H
Fructose
© Created by Alyssa 2023
B1.1.4—Form and function of monosaccharides
Glucose
Alpha vs Beta
Glucose:
Differentiate
Between the
Two
Galactose
• Most commonly found
in milk, but also found
in cereals.
• Galactose is also a
hexose sugar like
glucose.
• It has the same formula Galactosemia, which means “galactose in the blood,”
refers to a group of inherited disorders that impair the
C6H12O6 but is less sweet body's ability to process and produce energy from
galactose.
Fructose
• Fructose is another
pentose sugar
commonly found in
fruits and honey.
• It is the sweetest
naturally occurring
carbohydrate.
Ribose
• Ribose is a pentose sugar,
it has a pentagonal ring.
• It forms the backbone of
RNA.
• Deoxyribose differs as
shown in the diagram and
forms the backbone of
DNA.
H O H H O H H O H 1– 4 H O H
H H H 1 glycosidic 4 H
OH H OH H OH H linkage OH H
HO
OH HO OH
OH
HO
O OH
H OH H OH H OH H OH
H2O
CH2OH CH2OH
CH2OH
CH2OH
H O H O H H O H 1–2 O
H H H
1 glycosidic 2
OH H OH H HO OH H linkage
H HO
HO HO CH2OH HO O CH2OH
H OH OH H H OH OH H
H2O
Examples of
Disaccharides
Polysaccharides
Chloroplas
Starch
t
Amylose and
Amylopectin are
both forms of
1 m
starch and
made from
repeating
glucose units
Amylose
Amylopectin
2. Glycogen
• (C6H10O5)n :consists of glucose monomers.
• Condensation reactions link carbon atom 1 -
4 on the next α-glucose.
• Branches occur where a condensation
reaction instead links carbon atom 1 – 6.
• The molecule is compact.
• Glycogen is the major storage form of glucose
in animals.
• It is stored in the liver and some muscles in
humans. The molecule
varies in size,
• Glycogen is useful in cells for glucose, and typically it
consequently energy, storage. consists of 30,000
units
CH2O
H
O OH
4. Chitin
H
H
OH H
OH H
H NH
• Another important C O
CH
structural polysaccharide
3
walls of fungi
• Can be used as
surgical thread
5.
Glycoproteins
• A glycoprotein is a sugar-
protein molecule.
• Glycoproteins perform vital
biochemical and structural
functions.
• They enable cells to recognize
another cell as familiar or
foreign, which is called cell-cell
recognition.
• They also help cells attach to A glycoprotein is a compound containing carbohydrate (or
and bind other cells, which is glycan) covalently linked to protein. The carbohydrate may
be in the form of a monosaccharide, disaccharide(s).
called cell adhesion. oligosaccharide(s), polysaccharide(s), or their derivatives
(e.g. sulfo- or phospho-substituted).
© Created by Alyssa 2023
B1.1.7—Role of glycoproteins in cell–cell recognition
Using Visualization S
oftware
• Select the glucose molecule and identify the colors used to
represent carbon, hydrogen and oxygen atoms.
• Using the models identify and describe the differences between
glucose, sucrose and fructose.
• Look at the amylose model and zoom out from it. Describe the
overall shape of the molecule.
• Zoom in on the amylose molecule. Each glucose sub-unit is
bonded to how many other sub-units? Which carbons atoms used
to form the glycosidic bonds? Are there any exceptions to these
rules?
• Select the amylopectin model and zoom in on the branch point.
This glucose sub-unit is bonded how many others and which
carbon atoms are used for bonded compared with the un-
branched amylose molecule?
• Using a similar approach to that above investigate the structure of
glycogen and find the similarities and differences between it and
both amylose and amylopectin.
© Created by Alyssa 2023
B1.1.4—Form and function of monosaccharides
Circle the
Sugars:
Lipids
Structure of Lipids
O
H 3C (CH2)n C
Chain (or ring) of carbon and
OH
hydrogen atoms
Carboxylic group
Hormonal signaling.
Lipid
Functions Triglycerides may form a tissue layer around many key
internal organs and provide protection against physical
injury
• Triglycerides can be used as a long-term energy
storage source
• They are stored in specialized groups of cells called
adipose tissue
Triglyceride
3 Fatty Acid Chains + Glycerol
Triglycerides
Triglycerides –
Function
Triglycerides – Function
Triglyceride Levels
• In addition to serving as a source of
Less than 150
energy, triglycerides carry the fat- Normal
mg/dL
soluble vitamins (including vitamin
Borderline-high 150-199 mg/dL
K, an important nutrient in normal
blood coagulation). High 200-499 mg/dL
Energy Storage
Medium-term storage –
glycogen.
Types of Fats
1
Saturated – no double
bonds
2
Monounsaturated –
one double bond
3
Polyunsaturated –
more (2+) double
bonds
© Created by Alyssa 2023
B1.1.10—Difference between saturated, monounsaturated and polyunsaturated fatty acids
Saturated Fatty
Acids
• Have the
maximum number
of hydrogen Stearic acid
atoms possible
• Have no double
bonds
(a) Saturated fat and fatty acid
• Solid at room
temperature
Unsaturated Fatty
Acids
Unsaturated fatty
acids
• Have one or more double
bonds
• Liquid at room temperature
Types of unsaturated
Oleic acid fats:
• Trans
• Cis
(b) Unsaturated fat and fatty acid
cis double bond
causes bending
• Monounsaturated
• Polyunsaturated
Hydrophilic head
CH2 N(CH )
Phospholipi
Choline
3
CH2 3
O
O P O– Phosphate
d Structure CH2
O
CH CH2
Glycerol
O O
C OC O
Hydrophobic tails
Fatty acids
• Consists of a Hydrophilic
hydrophilic “head”
head
Hydrophobic
tails
H3 C CH3
CH3
• Lipids characterized by a
carbon skeleton consisting of
four fused rings HO