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Bio Info

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15 views12 pages

Bio Info

Uploaded by

kashyapnancy107
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Shri RamSwaroop Memorial

University

Bioinformatics
BBT 5703 Presented by –
Aditi Kashyap
Topic – A Brief about NCBI 202210902110019
BTech biotechnology
Introducing
NCBI – A
Powerhouse in
bioinformatics
What is NCBI?
• DATABASES • Research
The NCBI houses several The NCBI conducts
databases , including GenBank Research on biomedical
for DNA sequences and PubMed problems at the molecular
for biomedical literature. The level using computational
NCBI’s data is available online and mathematical methods
through the Entrez search
engine

• Collaboration
The NCBI collaboraters with academia, industry
, other governmental agencies , and several NIH
institutes.
NCBI Homepage
Biological databases
Protein databases Nucleotide databases
It has both sequences and It contains sequence
structure information of DNA and RNA
Example - PDB Example – GenBank
UniProt EMBL
SCOP& CATH DDBJ
NCBI' Core
Databases
PubMed GenBank Entrez

PubMed is a free GenBank is a Entrez is


online database public database integrated
that allows of DNA search and
users to search sequences and retrieval system
and retrieve biological , enabling
biomedical and annotations seamless access
life sciences to NCBI’s vast
literature collection of
data
Different databases in
DrugBank is a web Blast is a bio

NCBI
based database that informatics program
provides detained that compares
information about sequences to find
drugs , their targets. regions of
And their interactions similaritsimilarity

PubChem Drug Bank


Drug bank RCSB PDB BLAST

PubChem is the Rcsb pdb is a US data


world’s largest centre that provides
collection of freely access to 3d
accessible chemical structural data for
information biological molecules
PubMed
What it contains
PubMed has over Rules 01
37 million citations and
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How it’s used


PubMed is most widely used biomedical
literature databases in the world.

Who developed it
PubMed was developed and is
maintained by the National centre for
Biotechnology Information (NCBI)
What is GenBank
GenBank contains over 65 billion nucleotide
bases from more than 61 million individual
sequences.

How’s it used
GenBank is used for biodiversity
research, such as identifying animal
sequences from environmental
samples

How’s it accessed
GenBank is freely accessible and
there are no restrictions on its
use or distribution.
Entrez

Entrez can efficiencefficiently retrieve


related sequences, structure, and
references

Entrez provides a Unified interface to search


and access NCBI vast collection of databases
and resources
Leveraging NCBI for
Bio informatics
Data exploration

Reseach
NCBI’S databases and tools allow
researchers to access , analyze , and
integrate a vast array of biological
data

Collaboration and sharing


Ncbi fosters collaborations by
providing platforms for researchers
to share data , methods, and
findings

Advancing sciences
By providing NCBI’s resources,
researchers can accelerate
scientific discovery and drive
progress in the field of
bioinformatics
Thank you!

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