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EPITHELIUM

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Epithelial tissue

Presented by:
Dr: Farhana Rajpar
Assistant Professor
Deptt: of Antomy, LUMHS, Jamshoro
LEARNING OBJECTIVES
 At the end of the lecture students will be
able to:
 Explain the ways in which epithelia are

classified
 Distinguish between, simple, stratified, and

pseudo stratified epithelia


 List characteristics of squamous, cuboidal,

columnar, and transitional epithelia


 Identify some common surface

specializations of epithelia
Basic tissue types
 Human tissues are classified into four basic
types;
1. Epithelial tissue
2. Connective tissue
3. Muscular tissue
4. Nervous tissue
Main characteristics of the
four basic types of tissues
tissue cells ECM Main
functions
epithelial Aggregated Small amount Covering of
polyhedral cells surfaces, lining
of body cavities
and glands

Connective Several types of Abundant Support and


tissue fixed and amount protection
wandering cells

muscle Elongated Moderate movement


contractile cells amount

Nervous tissue Elongated none Transmission of


process nervous
impulses
Introduction of Epithelial
tissue
Epithelium is a collection of closely packed
cells with very small amount of intercellular
substance.
 Cover or line body surfaces(except

tooth),internal closed cavities including


vascular system(except articular surface)
and tubes that communicate with exterior .
 Epithelium itself is avascular(except stria

vascularis of inner ear), it is nourished by


diffusion from blood vessels in underlying
connective tissue.
Cont:
 All epithelia rest on a thin delicate, non
cellular layer called basement membrane
 It is arranged in the form of sheet called as

membranous epithelium or in glands called


as glandular epithelium.
Function of epithelial
tissues
 Protection (skin)
 Absorption (small and large intestine)
 Transport (by cilia)
 Secretion (gland)
 Excretion (tubules of kidney)
 Gas exchange (lung alveoli)
 Contractility (myoepithelial cells)
 Sensory (taste buds, olfactory and inner ear

cells)
Epithelial groups
 Two main groups of epithelia;
1. Covering or surface epithelium
2. Glandular epithelium
classification
 According to No: of cell layer
 Simple epithelium
 Stratified epithelium
 Pseudo stratified epithelium
 According to shape of cells
 Squamous
 Cuboidal
 Columnar
 Presence of surface specializations;
 Cilia, microvilli, stereocilia, keratin
Simple squamous epithelium
Features;
 Flat cells resting on basement membrane.
 Ovoid or flattened centrally placed nucleus.
 Involves in diffusion, secretion and

absorption.
 Examples;
 Endothelium
 Mesothelium
 Alveolar epithelium.
Simple cuboidal epithelium;
features:
 Single layer of cuboidal cells.
 Spherical centrally placed nucleus.
 Involves in secretion, absorption and

excretion.
 Examples;
 Distal convoluted tubules
 Surface of ovary
 Small ducts of glands and
 Thyroid follicle
Simple columnar epithelium
features;
 Layer of tall column shaped cells.
 Basally located oval nucleus, perpendicular

to basement membrane.
 Involves in absorption and secretion
 Two types
 Simple columnar ciliated E.g. uterine tubes

and uterus
 Simple columnar non ciliated E.g. Stomach,

gall bladder, and intestine.


Pseudo stratified columnar ciliated
epithelium
Features;
 Single layer of tall & short cells that gives

false impression of being stratified because


nuclei lies at different level.
 All cells rest on basement membrane but

not all cells reach the luminal surface.


 Examples;
 Conductive part of respiratory tract
 Eustachian tube, nasal cavity, nasopharynx,

paranasal sinuses
Stratified epithelium
Stratified squamous
epithelium
 Multiple layers of cells, highly protective.
 Only basal cells are lying on basement

membrane.
 Basal cells are cuboidal, which are

continuously dividing stem cells.


 Next to basal layer, few layers of large

polygonal cells.
 Surface cells are flattened (squamous).
St.epithelium
 depending on the shape of upper most layer
it is further subdivided into;
 Stratified squamous…divided in to two

types.
 Stratified cuboidal
 Stratified columnar
 Transitional epithelium
Stratified squamous
keratinized epithelium
 The surface cells are non nucleated, non
living layer, contain a tough protein known
as keratin (intermediate filament).
 Examples;
 Epidermis of skin
Stratified squamous non-
keratinized epithelium
 Keratin is not present on the surface cells.
 Examples;
 Lining of oesophagus
 Pharynx
 Oral cavity
 Vagina
 Uterine cervix
 Cornea
 Lower part of anal canal
Stratified cuboidal
epithelium
 Two to three layers of cuboidal cells.
 Examples;
 Ducts of sweat glands
 Larger excretory Ducts of salivary glands

and
 Growing ovarian follicles
Stratified columnar epithelium
 Upper layer of cells are columnar and
deeper are cuboidal.
 Examples;
 Conjuctival epithelium
 Epiglottis
 Parts of male urethra
 Main ducts of salivary glands
Transitional epithelium
 Special type of stratified epithelium.
 Several layers of cells but the no of cell

layers and shape of surface cells vary with


distended and non distended state of organ.
 In non distended state the no of cell layers

inc and shape of surface cells are dome


shaped or umbrella shape.
 In distended state the cell layers are

reduced and shape of surface cells are


flattened.
Examples of transitional
epithelium
 Lining of renal calyces
 Renal pelvis
 Urinary bladder
 Parts of male urethra and
 Ureters
 As this epithelium lines the most of urinary

passages, it is also called urothelium.

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