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    Classification of Renal Diseases

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    Nezmi N

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    Classification of Renal Diseases

    Uploaded by

    Nezmi N
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    12 views26 pages

    Classification of Renal Diseases

    Uploaded by

    Nezmi N

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 26

    Classification of renal diseases

    Dr Sajeevkumar.K.S
    MD,DM,FASN
    Professor Department
    of Nephrology,
    Medical
    college,Trivandrum
    compartments
    Glomerulus

    Tubulo interstitium

    Vascular compartment
    Symptoms&signs

     Hematuria

     Froathy urine

     Increased frequency of micturition

     Polyuria

     Oliguria

     gravelluria
     Anorexia

     Nausea,vomiting

     Breathlessness

     Altered sensorium

     Seizures

     pruritus
    signs
    Edema

    Hypertension

    Signs of fluid overload


    Classification of renal
    diseases
    Acute glomerulonephritis

     acute interstitial nephritis

    Acute kidney injury


    Chronic kidney disease

    Asymptomatic urinary abnormalities


    Glomerular diseases
    Glomerulas –mainly filtration barrier

    Diseases produce

    Hematuria[macroscopic/microscopic]
    Cola coloured urine
    Proteinuria[subnephrotic/nephrotic]
    oliguia
    Hypertension
    Edema
    Dyslipidaemia

    Deranged renal function


    Hematuria
    Can be frank hematuria
    or
    Microscopic hematuria

    painless

    RBC cast
    Proteinuria

    Proteinuria> 1 gm

    Can be nephrotic range


    oliguria
     less than 400ml/day

    Anuria<50 ml/day
    Edema

    Pitting pedal edema

    Facial puffiness

    Anasarca
    Hypertension

     BP More than 130/90mm of Hg.


    Types of glomerular diseases
    Acute glomerulo nephritis.

    Presents with oliguria,cola coloured


    urine,edma&fluid overload,hypertension .

    Hematuria,RBC cast,deranged renal


    function
    Chronic glomerulonephritis
    Edema
    Microscopic hematuria
    breathlessness
    Hypertension
    Deranged renal function
    Urine output drops later
    Nephotic syndrome
    Nephrotic range proteinuria
    >3.5 gm proteinuria.
    Hypoabuminaemia <3.5 gm S.Albumin

    Dyslipdaemia –increased S.Cholestrol

    Edema
    Deranged renal function
    How will you assess renal function?

    S.Creatinine

    Blood urea

    eGFR
    Glomerular diseases can
    produce
    Acute kidney injury

    Chronic kidney disease


    Diseases of
    tubulointerstitium
    Mainly involved in
    reabsorption,secreation,concentration&dilu
    tion of urine.

    Production of some hormones

    Parts are PCT,LH,DCT,CT,CD,Interstium.


    Reabsorption of solutes affected-
    Na,Potassium,Ca,Mg,Uric acid,Phosphorus.

    Production of erythropoietin,active vitD

    Concentrating capacity affected


    Can produce
    Acute kidney injury-non oliguric,BP normal

    Chronic kidney disease


    Symptoms&signs
    Polyuia
    Nocturia
    Fatigue
    Bone pain
    Bone deformities
    Usually no edema
    Hypertension absent till late
    Diagnosis usually missed
    Anaemia
    Deranged RFT
    Contracted kidneys in USS abdomen
    Usually slowly progressive

    Reaches ESRD in >10 yrs


    Questions ?

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