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Neurology 1

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HS834:

Neurology
part 1
Recorded lecture
Analisa Marie Pais
ap21904@essex.ac.uk

With Thanks to
María P. Miranda Rivera
Session outline

• Organization
• Central nervous system
• Peripheral nervous system
Central nervous system
(CNS)
Central nervous system (CNS)
• Brain and spinal cord
• Neural tissue—
- Communicating tissue (Neurons)
- Supportive tissue (Glial cells)
• Protected by supporting connective tissue
• Have complex blood supply
• Brain = “central station”
• Integrates, processes and coordinates sensory data
from sense receptors throughout the body*
• Initiates and controls motor action
• Meninges – surrounds and protects brain and
spinal cord

(Rouse, 2020, p. 36, fig 2-11)


Brain Fissure

• Centre for higher mental functions


• Cerebrum

• Hemispheres (Left and Right)


• Subdivided into lobes
• Corpus callosum

• Cortex: outer surface of hemispheres


• Gyrus
• Sulcus
• Fissure

(Mayfield Brain and Spine, 2018) (Mayfield Brain and Spine, 2018)
Cortex
Lobes of the brain and their subsections
• Frontal lobe:
• Cognitive functions, speech, expressive
language

• Parietal lobe:
• Touch perception and interpretation

• Temporal lobe:
• Receptive language and long-term memory

• Occipital lobe:
• Visual perception and interpretation
(Mayfield Brain and Spine, 2018)

(Rouse, 2020)
Frontal lobe
• Primary motor cortex
• Directs voluntary movements of skeletal
muscles

• Supplementary motor cortex


• Motor planning of speech

• Broca’s area (Inferior frontal gyrus)


• Paul Broca
• Controls movements involved in speech
production
Clinical note:
•Broca’s aphasia
•Apraxia of speech
Parietal lobe
• Primary somatosensory (sensory) cortex
• Receives and perceives sensory information
from the body
• touch, pressure, pain, vibration, temperature, taste

• Supramarginal gyrus
• Phonological processing for speech
• Conditions:
• Conduction aphasia
• Angular gyrus
• Role in written comprehension
• Agraphia
Clinical note:
• Reading, writing, naming
difficulties
Occipital lobe
• Primarily concerned with vision
• Lt visual field -> Rt visual cortex
• Rt visual field -> Lt visual cortex

Clinical note:
• Visual hallucinations
• Prosopagnosia
Temporal lobe
• Primary auditory cortex
• Receives sound stimuli from the acoustic
nerve

• Auditory association area


• Processes acoustic signals the brain
interprets as sound, speech, music

• Wernicke’s area (Broadman area 22)


• Carl Wernicke
• Comprehension of spoken and written
language Clinical note:
•Wernicke’s aphasia
https://www.dailynews.lk/2021/04/27/features/247558/role-brain-perception-and-production-language
Functional anatomy

Primary motor cortex - The


surface of the precentral
gyrus forms the primary
motor cortex. The neurons
of the motor cortex direct
voluntary movements by
controlling the motor
neurons in the brainstem
and spinal cord and so
effecting voluntary muscle
contraction and body
movement.
Primary sensory cortex- The surface of the
postcentral gyrus forms the primary sensory
cortex. Neurons in this region receive sensory
information about touch, pressure, pain, vibration,
temperature and taste.
Coronal view of the left primary Coronal view of the left primary
motor cortex and homunculus sensory cortex and homunculus

(Rouse, 2020, p. 183, fig 8-11) (Rouse, 2020, p. 184, fig 8-13)
What do these images tell us with regard to
the neurological control of swallowing?
Functional anatomy

Association areas
Somatic sensory- This monitors activity in the
primary motor cortex and is involved in the
recognition of information about touch.

Visual association area- Monitors patterns of


activity in the visual cortex and interprets the
results.

Auditory association- Monitors sensory


information in the auditory cortex

Somatic motor association area- This is


responsible for the coordination of learned
movements

The sensory and motor regions are connected to


association areas. These interpret incoming
data or coordinate a motor response. The
senses of smell, sight and hearing involve
separate areas of the sensory cortex and each
have their own association area.
Diencephalon
• Thalamus
• Sensory information
• Motor impulses
• Consciousness and alertness

• Hypothalamus
• “Linker and regulator” (Rouse, 2020, p. 133, fig 6-13)

• Subthalamus
• Epithalamus
• Optic Tract
• Third Ventricle
(Rouse, 2020, p. 137, fig 6-6)
Cerebellum
• “Little brain”
• Second largest brain region
• Composed of two hemispheres (hidden
by cerebellar cortex)
• Coordination of movement, precision
and accurate timing
• Balance and equilibrium, posture
(Rouse, 2020, p. 124, fig 5-35)

• Rapid and precise movements involved


for speech
Clinical note:
• Ataxia
• Ataxic dysarthria
• Hypotonia
Brainstem
• Third major division of the brain
• Connects spinal cord with brain
• Midbrain (mesencephalon)
• Motor and sensory functions: postural and visual
reflexes, eye movements
• Pons (metencephalon)
• Transmits movement information from cerebral
hemispheres to cerebellum (Rouse, 2020, p. 107, fig 5-14)

• Medulla (myelencephalon)
• Centres that control automatic bodily functions
• Very important for speech control

• Fourth Ventricle (Posterior to the Brainstem and


anterior to the cerebellum)
Clinical note:
• Locked-in-syndrome
(Physiology Plus, 2017)
Ventricles
• 4 cavities within the brain
• Each hemisphere has a large lateral
ventricle
• Remnants of the embryonic neural tube
• Production, transport and removal of
cerebrospinal fluid (CSF)
• Lubricates the CNS (brain and spinal cord)
• Protects brain against trauma
Cranial meninges
• 3 layers of protective tissue
• Dura mater
• Arachnoid mater
• Pia mater

Clinical note:
• Meningitis
Spinal cord
• Contained within the vertebral column
• Sensory and motor fibres within, transmit
information about movement, senses, reflexes
• Organized into 5 sections
• Spinal nerves, emerge from spinal cord
• Surrounded and protected by meninges

(Rouse, 2020, p. 94, fig 5-1)


Peripheral
nervous
system
(PNS)
Major divisions of the PNS
References 1
• J. Anthony Seikel, David G. Drumright, & Daniel J. Hudock. (2021). Anatomy &
Physiology for Speech, Language, and Hearing, Sixth Edition: Vol. Sixth edition.
Plural Publishing, Inc.
• Mayfield Brain & Spine (2018) Anatomy of the brain Available at:
https://mayfieldclinic.com/pe-anatbrain.htm
• Rouse, MH (2020) Neuroanatomy for speech-language pathology and audiology
Burlington: Jones & Bartlett Learning
• Physiology Plus (2017) Brainstem Available at:
http://physiologyplus.com/brainstem/
• Peate, I and Nair, M (2017) Fundamentals of anatomy and physiology: For
nursing and healthcare students Chichester: John Wiley & Sons Ltd

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