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    Pernicious Anemia

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    Tracy Pearl
    Pernicious anemia is a condition where the body cannot properly absorb vitamin B12 from food, leading to a decrease in red blood cells. Vitamin B12 is essential for red blood cell development and nervous system function. Intrinsic factor, produced by stomach cells, is required to absorb B12 in the small intestine. Lack of intrinsic factor causes B12 deficiency and megaloblastic anemia, where red blood cells are larger than normal. Symptoms include fatigue, pale skin, loss of appetite, and neurological issues. Treatment involves monthly B12 injections to correct the deficiency, along with a balanced diet containing nutrients for blood cell growth. Tests to diagnose include blood counts, B12 levels, and the Schilling test

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    Pernicious Anemia

    Uploaded by

    Tracy Pearl
    543 views7 pages
    Pernicious anemia is a condition where the body cannot properly absorb vitamin B12 from food, leading to a decrease in red blood cells. Vitamin B12 is essential for red blood cell development and nervous system function. Intrinsic factor, produced by stomach cells, is required to absorb B12 in the small intestine. Lack of intrinsic factor causes B12 deficiency and megaloblastic anemia, where red blood cells are larger than normal. Symptoms include fatigue, pale skin, loss of appetite, and neurological issues. Treatment involves monthly B12 injections to correct the deficiency, along with a balanced diet containing nutrients for blood cell growth. Tests to diagnose include blood counts, B12 levels, and the Schilling test

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    Pernicious anemia is a condition where the body cannot properly absorb vitamin B12 from food, leading to a decrease in red blood cells. Vitamin B12 is essential for red blood cell development and nervous system function. Intrinsic factor, produced by stomach cells, is required to absorb B12 in the small intestine. Lack of intrinsic factor causes B12 deficiency and megaloblastic anemia, where red blood cells are larger than normal. Symptoms include fatigue, pale skin, loss of appetite, and neurological issues. Treatment involves monthly B12 injections to correct the deficiency, along with a balanced diet containing nutrients for blood cell growth. Tests to diagnose include blood counts, B12 levels, and the Schilling test

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    543 views7 pages

    Pernicious Anemia

    Uploaded by

    Tracy Pearl
    Pernicious anemia is a condition where the body cannot properly absorb vitamin B12 from food, leading to a decrease in red blood cells. Vitamin B12 is essential for red blood cell development and nervous system function. Intrinsic factor, produced by stomach cells, is required to absorb B12 in the small intestine. Lack of intrinsic factor causes B12 deficiency and megaloblastic anemia, where red blood cells are larger than normal. Symptoms include fatigue, pale skin, loss of appetite, and neurological issues. Treatment involves monthly B12 injections to correct the deficiency, along with a balanced diet containing nutrients for blood cell growth. Tests to diagnose include blood counts, B12 levels, and the Schilling test

    Copyright:

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    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
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    PERNICIOUS ANEMIA

    PERNICIOUS ANEMIA
    a decrease in red blood cells that occurs when the body cannot properly absorb vitamin B12 from the gastrointestinal tract. Vitamin B12 is necessary for the proper development of red blood cells.

    VITAMIN B12
    also called cobalamin, is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. It is one of the eight B vitamins. It is normally involved in the metabolism of every cell of the human body.

    INTRINSIC FACTOR
    also known as gastric intrinsic factor (GIF) is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 later on in the terminal ileum.

    MEGALOBLASTIC ANEMIA
    megaloblastic anemia is a blood disorder in which there is anemia with larger-thannormal red blood cells.

    PATHOPHYSIOLOGY
    Predisposing Factors Age Race Family history Autoimmune disease Precipitating Factors Diet Surgery (removal of parts of stomach or small intestines) Drugs that affect the absorption of vit. B12

    Lack of intrinsic factor in the stomach


    Hypoxia Pallor Pail nail bed Loss of appetite

    Decrease in vit B12 absorption Decrease in production of red blood cell Abnormal red blood cell

    Disorientation Irritability and personality changes

    Dizziness Fatigue Headache Pale skin or pallor Poor concentration Shortness of breath Weakness

    Pernicious Anemia

    Dementia Depression Loss of balance Memory loss Numbness or tingling in arms or legs

    PERNICIOUS ANEMIA MANAGEMENT


    Monthly vitamin B12 injections are prescribed to correct the vitamin B12 deficiency. This therapy treats the anemia and may correct the neurological complications if taken early enough. In people with a severe deficiency, the injections are given more often at first. Some doctors recommend that elderly patients with gastric atrophy take vitamin B12 supplements by mouth in addition to monthly injections. There is also a preparation of vitamin B12 that may be given through the nose. For some people, taking vitamin B12 tablets by mouth in a very high dose can be an effective treatment. A well-balanced diet is essential to provide other elements for healthy blood cell development, such as folic acid, iron, and vitamin C.

    TEST TO IDENTIFY PERNICIOUS ANEMIA


    Bone marrow examination (only needed if diagnosis is unclear) Complete blood count (CBC) Schilling test Serum vitamin B12 level

    NORINE BARRIOS

    TRACY PEARL TEMPERATURA

    BSN 3-D

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