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    Dengue Autosaved

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    Maricris Pallar
    The document discusses dengue, a mosquito-borne viral infection caused by four distinct serotypes of dengue virus. It is transmitted to humans through the bites of the female Aedes aegypti mosquito. Symptoms include fever, headache, muscle and joint pain, and bleeding diathesis. There are four stages of dengue infection from febrile to bleeding diathesis to circulatory failure and shock. Diagnosis involves tests like tourniquet test, ELISA, and virus isolation. Treatment is symptomatic and includes rehydration and fever relief. Prevention relies on strategies to eliminate mosquito habitats and bites.

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    Dengue Autosaved

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    Maricris Pallar
    15 views12 pages
    The document discusses dengue, a mosquito-borne viral infection caused by four distinct serotypes of dengue virus. It is transmitted to humans through the bites of the female Aedes aegypti mosquito. Symptoms include fever, headache, muscle and joint pain, and bleeding diathesis. There are four stages of dengue infection from febrile to bleeding diathesis to circulatory failure and shock. Diagnosis involves tests like tourniquet test, ELISA, and virus isolation. Treatment is symptomatic and includes rehydration and fever relief. Prevention relies on strategies to eliminate mosquito habitats and bites.

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    What is Dengue ?

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    The document discusses dengue, a mosquito-borne viral infection caused by four distinct serotypes of dengue virus. It is transmitted to humans through the bites of the female Aedes aegypti mosquito. Symptoms include fever, headache, muscle and joint pain, and bleeding diathesis. There are four stages of dengue infection from febrile to bleeding diathesis to circulatory failure and shock. Diagnosis involves tests like tourniquet test, ELISA, and virus isolation. Treatment is symptomatic and includes rehydration and fever relief. Prevention relies on strategies to eliminate mosquito habitats and bites.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    15 views12 pages

    Dengue Autosaved

    Uploaded by

    Maricris Pallar
    The document discusses dengue, a mosquito-borne viral infection caused by four distinct serotypes of dengue virus. It is transmitted to humans through the bites of the female Aedes aegypti mosquito. Symptoms include fever, headache, muscle and joint pain, and bleeding diathesis. There are four stages of dengue infection from febrile to bleeding diathesis to circulatory failure and shock. Diagnosis involves tests like tourniquet test, ELISA, and virus isolation. Treatment is symptomatic and includes rehydration and fever relief. Prevention relies on strategies to eliminate mosquito habitats and bites.

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    of 12

    DENGUE

    VECTOR-BORNE BY:
    MARHEANE M. MONTALBAN
    DENGUE

     mosquito-borne viral infection caused by


    4-types of viruses.
    Found in tropical and subtropical climates worldwide, mostly in urban and
    semi-urban areas.
    Occurs year-round in the Philippines
    -Cases :July- Nov
    -Peak: Sept-Oct
    -Lowest: Feb-April
    CAUSATIVE AGENT
    - Arbo Viruses-dengue viruses comprises of 4
    distinct serotypes (DENV1-DENV4) which belongs
    to the genus Flavivirus, family Flaviviridae.

    MODE OF TRANSMISSION
    -the viruses are passed on to humans through the
    bites of an infected female Aedes agypti, w/c mainly
    acquires the virus while feeding on the blood of an infected
    person.
    -low-flying
    -tiger-look appearance
    -day-biting
    -seen in clear stagnant water.
    -4-10 days incubation
    SIGNS AND SYMPTOMS
     Vomiting COMPLICATION:
     Low platelet *Circulatory system failure
     Nausea *Dengue Shock Syndrome
     Onset of fever
     Severe HA
     Pain of the muscle and joint
     Abdominal pain
     Rashes
     Diarrhoea
     Bleeding diathesis such as: positive tourniquet
    test, petechiae, epistaxis, hematemesis,
    thrombocytopenia
    STAGE 1”Febrile Stage” STAGE 2 “bleeding diathesis
    -fever 3 days -epistaxis
    -abd’l pain -hematemesis
    -(+)Tourniquet test -bleeding of gums
    -Joint pain -melena
    -Headache -thrombocytopenia

    STAGE 3
    Circulatory failure
    Stage 4
    -Dengue Shock Syndrome
    MODIFIABLE PATHOPHYSIOLOGY NON-MODIFIABLE
    Gender, Age
    Environment uncovered stock water

    Bites of the Aedes aegypti

    Virus penetration to the skin

    Virus infects and replicate inside the Langerhans cell

    Langerhans cell release interferon

    Infected Langerhans cell go to the lymphatic

    Then goes to the circulation, results to Viremia

    Activation of Immune response Lymphocytes

    Neutrophils and WBC

    Release of Pyrogen

    Reset of Hypothalamus Fever Increase Blood Pressure in the vessel


    Dengue infection

    Antibody Formation

    Reinfection

    Augmentation of virus multiplication

    Increased vascular permeability


    Reduced platelets

    Plasma leakage
    Coagulopathy

    Hypovolemia
    DIC

    Shock
    Severe bleeding

    Death
    Lab Diagnosis and Exam
    • Tourniquet test(capillary fragility or Rumpel Leads Test)
    -presumptive test w/c is positive in the presence of more than 20 petechiae within an
    inch square
    • Confirmatory rapid test- ELISA
    • Gold standard- Virus isolation or molecular methods.
    • Guaiac testing- occult blood in the stool

    The ff. should also be performed in the workup in the patients with possible dengue:
    -CBC
    -Metabolic Panel
    -serum protein and albumin levels
    -liver panel
    -Coagulation panel with or without DIC
    MANAGEMENT
    1. Symptomatic and supportive relief
    2. Oral rehydration like oresol and IV fluids
    3. Paracetamol (DO NOT GIVE ASPIRIN!)
    4. Fresh whole blood and platelet transfusion as ordered if
    thrombocytopenia and platelet declined.
    5. For nosebleed, flex neck to prevent aspiration.
    6. Avoid unnecessary movement.
    7. Avoid giving dark foods.
    8. Provide warmth.
    9. Monitor vitals signs especially temperature.
    10.Assist in the management of shock (dorsal recumbent to T-position)
    PREVENTION:
    4-S Strategies of DOH:
    • Search and destroy
    • Seek early consultation
    • Self protection measures
    • Say YES to fogging only
    if during outbreak.
    *4 O’clock habit
    *”Tepok Lamok, Dengue Sapok”
    (September)

    **DENGUE VACCINE****
    THANK YOU!! 
    REFERENCES:

    • Philippine-Dengue/www.iamat.org
    • Slideshare.com

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