Dosage Forms

Download as pptx, pdf, or txt
Download as pptx, pdf, or txt
You are on page 1of 35

Dosage Forms

Waheed Iqbal (MPhil Pharmacology) (PhD scholar Pharmacology)


Department of Pharmacology, KMC Peshawar
Dosage form
 Are Pharmaceutical drug products in the form in which they are
marketed for use, with a specific mixture of active and inert ingredients
OR
 Dosage form are finished pharmaceutical products intended for
human or animal use e.g Panadol (paracetamol), Brufen (ibuprofen)
etc.
Dosage forms are classified on the basis of
Route of
Physical form
administration
Oral Solid

Parenteral
Semi solid
Inhaled
Liquid
Topical
Others (Ophthalmic, Gaseous
Otic, Rectal, vaginal)
Oral Dosage forms
Tablets
Solid Capsules
preparation Sachets
Lozenges
Pills
Powder
Syrups
Liquid Suspension
preparation Emulsion
Elixirs
Linctus
Mixtures
Tablets
 A Tablet is hard, compressed medication in
round, oval, square shape or any other shape.
 It’s a solid dosage form that contain unit dose
of one or more medicaments.
 The tablets are prepared by mould or
compression method.
Capsules
Medicinal substances enclosed in a shell. Drugs having unpleasant taste are
given by this method. Capsules have two types.

1. Hard Gelatin Capsule 2. Soft Gelatin Capsule


Sachets
Sachets are small sealed bag or packet
containing drug powder. They are
usually intended to be dissolved in
water prior to use.
Lozenges
• Solid dosage form in which the
medications are intended to be
dissolved in mouth.
• They are used to lubricate and soothe
the irritated throat (sore throat).
Pills
Spherical or oval masses containing
one or more medicinal substances.
Maximum weight being 300mg.
They are usually sugar coated for
e.g.
Oral contraceptives
Liquid preparations

Suspension
Heterogeneous mixture in which particles
of insoluble drugs are kept suspended by
means of a suitable suspending agent like
gum acacia or gum tragacanth.
Emulsion
Liquid preparations containing
2 immiscible liquids i.e.(water
and oil) which are made
miscible by the help of suitable
emulsifying agents (Tragacanth).
Syrups
Clear Concentrated aqueous
solution of sucrose or other sugar
to which medicinal substances
and flavoring agents are added.
Elixirs
Pleasantly flavored and are
sweet liquid preparations.
They contain a high proportion
of alcohol or glycerin or
propylene glycol .
Linctus
Thick viscous preparations
containing sucrose and medicinal
substances. They possess demulcent,
expectorant and suitable sedative
properties. They are mainly used for
cough relief.
Mixtures
Liquid preparations containing
one or more drugs dissolved
in an aqueous vehicles. They
are usually flavored for
internal administration.
Parenteral Dosage form
Injections
 Either sterile solutions or suspension.
 They are used to administer the drugs which may become inactive
when given orally or drugs with high 1st pass metabolism
 In emergency situations or patient is unconscious or having vomiting
and diarrhea
 Injections are also used for the treatment as well as diagnostic
purposes
continue
Consist of Ampoules, vails and/or infusion. The different routes are
Subcutaneous
 Intramuscular
 Intravenous
 Intrathecal (spinal canal or subarachnoid space)
 Intraarticular (injection in joints)
 Intra-arterial (injection in artery)
Inhalation dosage form
• Including drugs that are given directly through
respiratory passages.
• It includes..
AEROSOLS:
Consist of solution or suspension of medicinal substance in a mixture of
inert propellants, which is held under pressure in an aerosol dispenser,
which consist of suitable container fitted with a valve e.g. Sorbitol
aerosol.
Sprays
Preparation of medicinal substance in aqueous, alcoholic or glycerol
containing media to be applied to the nose or throat by means of an
automizer. They are absorbed from respiratory epithelium.
Inhalers
• Liquid preparations composed of volatile ingredients in a specially
designed container under pressure which when pressed the drug is
inhaled, are absorbed through respiratory epithelium and has local
effect.
Inhaler Aerosol Spray
Topical Dosage forms
• Intended to be applied externally to the skin. It includes
• Lotions
• Creams
• Ointments
• Liniments
• Pastes
• Poultices
Lotions
Liquid preparations for application
to skin. Lotions may be
emulsions, suspensions or
solutions. They are not to be
rubbed. It can be applied with
brush e.g. Calamine lotion
Creams
Viscous emulsions of semi solid
consistency which may be oil in
water or water in oil type. They
are prepared with the help of
suitable emulsifying agent.
Ointments
Semi solid preparations
consisting of an active
ingredient dissolved or
dispersed in a suitable
base.
Liniments
These are medicated
topical preparations for
application to the skin by
rubbing. They are also
called balm or heat rubs.
Poultices
Thick pasty preparations
applied to the skin with the
objective of reducing pain
or inflammation.
Other dosage forms
• Ophthalmic
• These are the dosage forms intended for application into the eyes and
includes
• Eye drops
• Eye ointments
Eye drops
Sterile solutions or suspensions
for instillation into the eyes. They
usually contain substances with
antiseptic ,anti-inflammatory,
Anti-biotic, mydriatic and miotic
properties .They are also used for
Treatment and diagnostic
purposes.
Eye Ointments
Sterile drugs used for
application to the conjunctival
sac or eyelid margins. They
usually contain substances with
antiseptic ,anti-inflammatory,
Anti-biotic properties .
Otic
preparation
These are products applied to
or in the ear to treat conditions
of the external and middle ear.
They are similar to eye drops
Rectal
preparation
Rectal solutions, emulsions and
suspensions are liquid or solid
preparations intended
for rectal application to obtain
a local or systemic effect, or
they may be intended for
diagnostic purposes.
continue
• Enemas (liquid preparations)
• Suppositories (solid
Preparations)
Vaginal Preparations

• Pessaries
• These are solid bodies suitably
shaped for vaginal
administrations and contain
drugs which acts locally e.g.
Nystatine Pessaries (antifungal
drug).
THANK YOU

You might also like