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PRESCRIPTION

Mr. DINESH SHAKYA


Assistant Professor
Faculty of Pharmaceutics
Jain College,Gwalior
CONTENTS
INTRODUCTION OF PRESCRIPTION
PARTS OF PRESCRIPTION
TYPES OF PRESCRIPTION

HANDLING OF PRESCRIPTION
ERROR IN PRESCRIPTION
INTRODUCTION
 It is an order by a physician, dentist,
written
veterinarian or a registered medical practitioner
(RMP) to a pharmacist to compound and dispense a
specific drug for the patient. OR
 Prescription is a written order for medication, issued
by physician or RMP. Prescription is relationship
between physician and pharmacist.
Physician (RMP) Pharmacist patients
PARTS OF A
PRESCRIPTION
A typical prescription consists of the following parts:
1. Prescriber office information
2. Date
3. Patient information (Name, Age, Sex And Address Of The
Patient)
4. Superscription (symbol ℞)
5. Inscription (Medication prescribed)- Main part of prescription
6. Subscription(Direction to Pharmacist/Dispenser )
7. Signatura or Transcription (Direction for Patient)
8. Renewal instructions
9. Prescriber’s signature and registration number.
1.Physician (Prescriber) office Information:
Information about physician is essential so that the patient
could be contact in emergency. Following information is
mentioned on the prescription
i. Doctor's or office name.
ii. Address with phone number and e-mail.
iii. Prescription number, (required calling the
when
pharmacy for a refill)
2. Date
It helps a pharmacist to find out the date of
prescribing.
It also helps in know when the medicines were last
dispensed if the prescription is brought for
redispens.
In case of habit forming drug the date prevents
the misuse of the drug by the patient
3. Patient information
PATIENT INFORMATION (Name, Age, Sex and
Address of the Patient)
Name and address of the patient for identification
purpose.
Age and sex of the patient is required for child
patient to check the prescribed dose.
4. SUPERSCRIPTION (symbol ℞)
It is represented by ℞ (Latin term)
„recipe‟ which means „take thou‟ or „you take‟.
In olden days, the symbol was
considered to be originated from the sign of
Jupiter.
Jupiter is the Greek God of healing.
This symbol was use for requesting God for the quick
recovery of the patient.
5. INSCRIPTION (Medication prescribed)
It is the main part of the prescription.
It contains the names and quantities of the prescribed
medicaments.
The medicament may be official preparation or nonofficial
preparation.
a.) Official preparation (i.e. from pharmacopoeia) – Only
name of the preparation is written E.g. Piperazine Citrate
Elixir IP
b.) Nonofficial preparation- Quantity of each ingredient
will be given and type of preparation will also be given
6. SUBSCRIPTION (Direction to Pharmacist)

In this part the prescriber gives direction to the


pharmacista) Regarding the dosage form to be
prepared.
b) Number of doses to be dispensed.
7. SIGNATURA (Direction for
Patient)
To be placed on the label.
It is usually written as „Sig.‟.
The signatura written in english and use
some
Latin abbreviations like t.i.d (thrice a
day),
b.i.d (twice a day) and o.d (once a day).
Cont..
Instructions should be written on the label of container so that
the patient can follow them.
The instructions may include-
a) Quantity to be taken(dose of drug)
b) Frequency and timing of administration of the
preparation
(dose interval)
c) Route of administration
d) Special instruction (if any)
8. RENEWAL
INSTRUCTIONS
The number of times a prescription is to be repeated is
written by the physician.
It is very important for the case of habit forming drugs
to prevent its misuse.
9. PRESCRIBER’S SIGNATURE AND
REGISTRATION NUMBER

The prescription must be signed by the

prescriber by his / her own hand.

Registration number should be written

in the case of dangerous and habit

forming drugs.
TYPES OF PRESCRIPTION
Prescriptions can be classified as
a) Compounded prescription

b) Noncompounded prescription
a). Compounded prescription-
Also known as extemporaneous prescription.
It is an order that requires mixing
of one or more ingredients (active
medicaments).
It contains several ingredients which
are divided into the following parts:
(a) Base: The active medicaments (Produce
the therapeutic effect).
(b) Additives-1) It enhances the action of the drug.
Cont…
2) It makes the preparation more elegant (attractive)
and palatable.
(c) Vehicle: It is the main carrier of the drug. E.g. -In
liquid preparations solvent (water) used as vehicle.
Now a day’s compounding is omitted from
prescription.
E.g. Sodium bicarbonate -3g
Simple Syrup -6ml
Purified Water (q.s.)-
100ml
b).Non-compounded
prescription
Does not require compounding of
pharmaceutical

product.

Precompounded drugs supplied by a

pharmaceutical company by its official or

proprietary name.
example
Latin Terms Latin term / phrases
Abbreviation
Semel in die or omne in o.d. Once a day
die

Bis in die, Bis die b.d Twice a day

Ter in die, Ter die t.i.d Thrice a day

Quartar in die q.i.d., q.d Four times a day

Si opus sit s.o.s When required


HANDLING OF PRESCRIPTION
The following procedures should be adopted by the
pharmacist while handling the prescription for
compounding and dispensing:
I. Receiving
II. Reading and checking
III. Collecting and weighing the materials
IV. Compounding, packaging and labeling
I. Receiving
The prescription should be received by the pharmacist.
While receiving a prescription, a pharmacist should
not change his/her facial expression.
It gives an impression that he/she is confused or
surprised after seeing the prescription.
II. Reading and checking
After receiving the prescription it should be
screened behind the counter.
Prescription authenticity should be checked.
The signature of the prescriber and the date of prescription
should be checked.
The pharmacist should read all the lines and words of the
prescription.
He/she must not guess any word.
If there is any doubt, the pharmacist
shouldconsult with the other pharmacist or the
prescriber over telephone.
(III). Collecting and weighing the material

Before compounding a prescription all the materials


should be collected from the shelves or drawers.
All the materials kept in the left hand side of the
balance. After measuring each material should be
kept on the right hand side of the balance.
IV. Compounding, packaging and labeling

Only one prescription should be compounded at a time.


Compounding should be done on a clean table.
All equipment required should be cleaned and dried.
The preparation should be prepared according to the
direction of the prescriber or as per methods given in
pharmacopoeia or formulary.
The compounded preparations should be filled in
suitable containers.
Label the container.
4. Communication failure
Failures during the process of patient management -
Includes illegible handwriting, incomplete
prescribing order. Common errors include: „g‟
mistaken for „mg‟
5.Dosage form of the drug prescribed

Many drugs are available in more than one dosage

forms. E.g. liquid, tablets, injections or suppositories.

The dosage form intended for the patient must be

mentioned in the prescription to reduce ambiguity.


6.Dose
If unusually high or low dose is mentioned in the
prescription then it must be consulted with the
prescriber. Some time a sustained release (SR) dosage
form is prescribed thrice or more times daily.
Actually SR dosage forms should be given once or
twice a day.
7.Instructions to the patient
Some times the instruction for a certain
preparation is either omitted of mentioned
partially. The route of administration should be
mentioned clearly.
8. Incompatibilities
It is essential to check that there are no pharmaceutical
or therapeutic incompatibilities in the prescription. If
more than two medicines are prescribed then it is the
duty of the pharmacist to see whether their
interactions will produce any harm to the patient or
not. Certain drugs have interactions with food. E..g,
Tetracycline should not be taken with milk or antacid.
LABELING OF DISPENSED
MEDICINES
After dispensing the medicine in a container, a label is
attached by adhesive. The label on the dispensed
medicines should provide the following
information:–
1. Name of the preparation-
When the prescriber mentions the name in the
prescription the same name must be displayed on
the label.
Example
PIPERAZINE CITRATE ELIXIR IP
If it is a non-official preparation then the name of the
dosage form should be given on the label.
e.g. THE MIXTURE, THE EMULSION,
THE DUSTING POWDER
Cont…
2. The strength of the medicine-
The strength of the active ingredient in the
preparation must be displayed if it is intended for
internal (oral) purpose. The amount in each unit of
dose should be mentioned.
e.g. In case of oral liquids “Each 5ml contains
250mg”
e.g. In case of tablet “Each tablet contains 500mg”.
Cont..
The values must be written in whole numbers and if
decimal is not avoidable then a zero is placed before
the decimal point. E.g. instead of 0.1g it should be
100mg, and instead of .5% it should be 0.5%. In case
of an official preparation the strength is not required
to be given, because the name with reference to the
pharmacopoeia is sufficient.
E.g. CHLORAMPHENICOL ORAL
SUSPENSION IP.

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