Inflammation
Inflammation
Slpbpa-203
Bsott-124
Bsabpa-203
INFLAMMATI
ON
LEARNING OBJECTIVES:
What is inflammation
How is it divided
Hemodynamic changes
A protective response involving host cells,
blood vessels and proteins
– Goals are: • eliminate the initial cause of
cell injury • Remove necrotic cells and
tissue • Initiate the process of repair
Types of Inflammation
Divided into acute and chronic
inflammation
ACUTE INFLAMMATION
BASIC PRINCIPLES
A. Characterized by the presence of
• Hemodynamic changes
• Neutrophils
bradykinin, etc.)
Hemodynamic changes
a. Initial vasoconstriction
b. Massive vasodilatation
A. Step 1-Margination
l. Vasodilation slows blood flow.
l. Selectins
l. Consumption of pathogens or
necrotic tissue
Step 6-Destruction of
phagocytosed material
3. Abscess formation
Dolor (pain)
Calor (heat)
Rubor (redness)
Tumor (swelling)
Hemodynamic changes
REFERENCES
Robbins Basic Pathology - 10th Edition – Elsevier
Short Textbook of Pathology by Inam
Danish - 2nd Edition
Caseating granuloma T.B.