Cleft Lip & Palate

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Cleft lip & palate

Maxillofacial Surgery
Children & Adolescent
10thSemester
Koorosh Arshi
Introduction
● Congenital abnormal space or gap in the upper lip, alveolus & palate.
● Most common of the craniofacial anomalies.
● Clefts of the lip occur more commonly in males than in females.
● Left side are more involved than right side.
● unilateral cleft lips are more common than the bilateral cleft of the lip.
● Bilateral clefts of the lip are most often associated with clefting of both
the primary and secondary palates.
Embryology
● At approximately 6 weeks of embryologic development the median nasal
prominence fuses with the lateral nasal prominences and maxillary prominences
to form the base of the nose, nostrils, and upper lip (primary palate).
● When this mechanism fails, clefts of the lips occur.
● At approximately 8 weeks the palatal shelves elevate and fuse with the septum
to form the intact secondary palate.
 When one palatal shelf fails to fuse with the other components, then a unilateral
cleft of the secondary palate occurs.
 If both of the palatal shelves fail to fuse with each other and the midline septum,
then a bilateral cleft of the palate occurs.
Classification
● Isolated cleft lip
● Cleft lip & palate:
 Unilateral or bilateral
 Complete or incomplete
● Isolated cleft palate
Cleft lip classification

● Class I: a unilateral notching of vermilion not


extending into lip.
● Class II: a unilateral notching of vermilion border,
with cleft extending into lip but not including the
floor of the nose.
● Class III: a unilateral clefting of the vermilion border
of the lip extending into the floor of the nose.
● Class IV: any bilateral clefting of the lip, whether it
be incomplete notching or complete clefting.
Veau Classification cleft lip & palate
 Class I : Defects of the soft palate only
 Class II : Defects involving the hard palate and soft palate.
 Class III : Defects involving the soft palate to the alveolus
on one side, usually involving the lip.
 Class IV : Defects involving both soft and hard palates
and continues through the alveolus on both sides.
Etiology
 Main cause is unknown.
 Multiple factors:
 Genetic
 Chemical exposures: alcohol consumption , smoking
 Radiation
 maternal hypoxia
 Teratogenic drugs: Retinoic acid, anti epileptic drug ,methotrexate
 Nutritional deficiencies : folic acid & vitamin A deficiency
 Physical obstruction,
 Infections: rubella virus during pregnancy
 Syndromes are associated cleft palate & lip: Vander Woude’s syndrome,
Treacher collins syndrome , Pierre Robin syndrome .
COMPLICATIONS
● Difficulty in Feeding:
● Cleft Palate may cause formula or breast milk to be accidently taken up
into the nasal cavity
● Inability to create negative pressure inside oral cavity
● Frequent nasal regurgitations
● inefficient handling of secretions and foodstuffs
● Upper respiratory tract infections
● Dental problems:
● Congenitally Missing teeth, Hypodontia , crowding
● Poor periodontal support, early loss of teeth
● Nasal Deformity , Esthetic
● Hearing issue & Recurrent otitis media
● Speech Difficulties: Velopharyngeal Insufficiency (VPI)
Diagnosis
● Ultrasound imaging: Currently ultrasound images of clefts of the lip can
be visualized as early as 16 weeks.
● Clinically evident at the birth
● MRI: evaluation of associated extra/intracranial abnormalities
Treatment planning & Timing
● Use special nipples to allow the baby for feeding properly
● Primary cleft lip repair : After 10 weeks (3 months)
● Cleft palate repair : 9–18 months
● Pharyngeal flap or pharyngoplasty: 3–5 years or later
based on speech development
● Maxillary/alveolar reconstruction with bone grafting: 6–9
years based on dental development
● Cleft orthognathic surgery: 14–16 years in girls, 16–18
years in boys
● Cleft rhinoplasty: After age 5 years but preferably at
skeletal maturity; after orthognathic surgery when possible
● Cleft lip revision: Anytime once initial remodeling and scar
maturation is complete but best performed after age 5 years
Cleft Lip Repair Cleft Palatal Repair Pharyngeal flap or pharyngoplasty

Maxillary/alveolar reconstruction with bone grafting Cleft rhinoplasty Cleft lip revision
Cleft orthognathic surgery
Thanks

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