Pharma

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Drug Name

biperiden

General Action

Specific Action

Indications

Antiparkin Anticholinergic activity Adjunct in the therapy sonian in the CNS that is of parkinsonism (postbelieved to help encephalitic, normalize the arteriosclerotic, and hypothesized imbalance idiopathic types) of cholinergic and dopaminergic Relief of symptoms of neurotransmission in extrapyramidal the basal ganglia in the disorders that brain of a parkinsonism accompany patient. Reduces phenothiazine therapy severity of rigidity and to a lesser extent, akinesia and tremor characterizing parkinsonism; peripheral anticholinergic effects suppress secondary symptoms of parkinsonism, such as drooling.

Contraindications

Side Effects

Nursing Responsibilities
Observe 10 Rs Decrease dosage or discontinue temporarily if dry mouth makes swallowing or speaking difficulty Give with meals if GI upset occurs; give after meals after meals if drooling or nausea occurs Ensure that patient voids just before receiving each dose of drug if urinary retention is a problem.

Contraindicated to patients with CNS: disorientation, hypersensitivity to biperidine confusion, hallucinations psychoses, agitation, excitement, depression CV: tachycardia, palpitations EENT: blurred vision, diplopia GI: dry mouth, constipation, nausea, vomiting, epigastric distress GU: urinary retention, decreased sweating, muscular weakness

Drug Name
Clozapine 100mg 1tab 1 /2 tab OD, HS

General Action
Antipsychotic Dopaminergic blocker

Specific Action
Blocks dopamine receptors in the brain; depresses the RAS; anticholinergic, antihistaminic, alpha-adrenergic blocking activity may contribute to some of its therapeutic (and adverse) actions. Clozapine produces fewer extra pyramidal effects than other antipsychotics.

Indications
Management of severely ill schizophrenics who are unresponsive to standard antipsychotic drugs. Reduction of the risk of recurrent suicidal behavior in patients with schizophrenia or schizoaffective disorder

Contraindications
Contraindicated with allergy to clozapine

Side Effects
CNS: drowsiness, sedation, seizures, dizziness, syncope, headache, restlessness, agitation CV: tachycardia, hypotension GI: nausea, vomiting, constipation, abdominal discomfort, dry mouth Hematologic: agranulocytosis Other: fever

Nursing Responsibilities
Observe 10 Rs Monitor temp, if fever occurs, rule out underlying infection, and consult physician for comfort measures. Encourage voiding before taking drug to decrease anticholinergic effects of urinary retention. Educate patient on seriousness of potential agranulocytosis.

Drug Name
Carbamazipine 200mg 1tab BIB

General Action
antiepileptic

Specific Action
Antiepileptic activity may be related to its ability to inhibit polysynaptic responses and block post-tetanic potentiation.

Indications
Treatment of acute manic and mixed episodes associated with bipolar 1 disorder

Contraindications
Contraindicated with hypersensitivity to carbamazipine

Side Effects

Nursing Responsibilities

CNS: dizziness, Observe 10 Rs drowsiness, Give drug with food to unsteadiness, prevent GI upset disturbance of Ensure that patient coordination, swallows RE tablets depression with whole-do not cut, agitation, speech crush or chew.do not disturbance discontinue drug CV: heart failure, abruptly or change increased hypotension dosage, except on the GI: nausea, vomiting, advice of the massive hepatic physician. cellular necrosis with total loss of intact liver tissue GU: urinary frequency, oliguria with hypertension, renal failure Respiratory: pulmonary hypersensitivity

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