Ventilator-Associated Pneumonia Add

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Bacterial Pneumonia

Prevention of
Ventilator-Associated
Pneumonia
Bacterial Pneumonia

 Abnormal inflammation of the lung caused by


bacteria….often characterized by
inflammation of the alveoli and abnormal
alveolar filling with fluid.
 Most common cause is Streptococcus
pneumoniae
 Caused by Gram positive and Gram negative
bacteria
Bacterial Pneumonia

 Various categories of nosocomial bacterial


pneumonias:
- Health care associated pneumonia
- Community acquired pneumonia
- Hospital acquired pneumonia
- Ventilator-associated pneumonia
What is Ventilator-associated
Pneumonia (VAP)?

 Ventilator-associated pneumonia (VAP) is the most


prevalent nosocomial infection in ICUs worldwide. It
accounts for 47% of all hospital acquired infections.
 VAP is pneumonia contracted after 48 hours on a
mechanical ventilator.
 About 15% of patients on ventilators contract VAP
 Mortality rate of 27-76%
Early-Onset VAP vs. Late-Onset VAP

 Early Onset VAP occurs from 3-7 days on a


ventilator. Etiologic agents: Staphylococcus aureous,
Haemophilus influenza, and Streptococcus
pneumonia. All Gram positive.
 Late-Onset VAP occurs from 5-7 days on ventilator.
Most fatal type. Etiologic agents: Pseudomonas
aeruginosa, the Acinetobacter species, the
Enterobacter species , and Stenotrophomonas
maltophilia. All Gram negative
Causes & Risks

CAUSES RISKS
Aspiration of bacteria into Tracheal Intubation
oropharynx
Length of time on
Colonization of bacteria in mechanical ventilation
respiratory and
gastrointesinal tracts Prior antibiotic therapy

Nasogastric tube
Prevention

 Nonpharmacological Strategies
– Non-invasive ventilation; semi-recumbent
positioning at 30-40 degree angle; adherence to
correct hand washing procedures; maintenance of
endotracheal tube cuff pressure; orotracheal tube
use instead of nasal tube use; continuous
subglottic suctioning; utilizing the LoTrach
tracheal tube.
Prevention continued…

 Pharmalogical strategies:
– antibiotic administration -prophylactic as well as
combination therapy, pneumonia vaccines,
selective digestive tract decontamination with
topical antibiotics, administration of stress ulcer
drugs, and using Chlorhexidine oral rinse.
Ventilator Bundles

 “A grouping of best practices with respect to


a disease process that individually improve
care, but when applied together result in
substantially greater improvement” (IHI,
2007)
 Proven to prevent or reduce the rate of VAP
in many hospital environments
Ventilator Bundle Components

 Semi-recumbent positioning of the patient


 Daily interruption of sedation
 Daily assessment of readiness of weaning
 Deep vein thrombosis and peptic ulcer
prophylaxis
Easiest way to prevent VAP

 Educate physicians and nurses to WASH


THEIR HANDS
 Recent studies indicated about a 50%
compliance with hand washing guidelines
 Education programs have helped increase
compliance to 89% but lasting effects
unknown
References

 Institute of Health Improvement. www.ihi.org


 Burger, C. D., & Resar, R. K. (2006, June).
"Ventilator bundle" approach to
     prevention of ventilator-associated
pneumonia [Letter to the editor].
     Mayo Clinic Proceedings, 81(6), 849-50

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