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Application of Computers in Science and Research

Computers are significantly applied in science and research, especially in bioinformatics. Bioinformatics uses information technology to store, organize, and analyze vast amounts of genetic sequence data and protein structures that are too large for the human brain to comprehend. Early databases of protein sequences from individual labs consolidated into public databases like SWISS-PROT, now containing over 70,000 sequences. Computers and software tools are widely used to generate and study these databases in order to further research like identifying protein function and coding regions in nucleic acids.

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Kimberly Raymundo
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269 views8 pages

Application of Computers in Science and Research

Computers are significantly applied in science and research, especially in bioinformatics. Bioinformatics uses information technology to store, organize, and analyze vast amounts of genetic sequence data and protein structures that are too large for the human brain to comprehend. Early databases of protein sequences from individual labs consolidated into public databases like SWISS-PROT, now containing over 70,000 sequences. Computers and software tools are widely used to generate and study these databases in order to further research like identifying protein function and coding regions in nucleic acids.

Uploaded by

Kimberly Raymundo
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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APPLICATION OF

COMPUTERS IN
SCIENCE AND
RESEARCH
• One of the significant application of computers
for science and research is evident in the field of
bioinformatics.

• Bioinformatics is the application of information


technology to store, organize, and analyze vast
and structures of proteins- the building blocks of
organisms and nucleic acids- the information
carrier (Madan, n.d.).
• Early interest in bioinformatics was
established because of a need to create
databases of biological sequence. The
human brain cannot store all the genetic
sequences of organisms and this huge
amount of data can only be stored,
analyzed, and be used efficiently with the
use of computers.
• While the initial databases of protein sequences
were maintained at individual laboratories, the
development of a consolidated formal database,
known as SWISS-PROT protein sequence
database was initiated in 1986.

• It now has about 70,000 protein sequence from


more than 5,000 model organisms, a small
fraction of all known organisms.
• The enormous variety of divergent data
resources is now available for study and
research by both academic institutions and
industries. These are made available as public
domain information in the larger interest of
research community through the Internet (
www.ncbi.nlm.nih.gov) and CD-ROMs (on
request from www.rcsb.org). This databases are
constantly updated with additional entries
(Madan, n.d.).
• Computers and software tools are widely
used for generating these databases and to
identify the function of proteins,
determine the coding (useful) regions of
nucleic acid sequences, find suitable drug
compounds from a large pool, and
optimize the drug development process by
predicting possible targets
Some of the software tools which are
handy in the analysis include: BLAST
(used for comparing sequences);
Annotator (an interactive genome analysis
tool); and GeneFinder (tool to identify
coding regions and splice sites) (Madan
n,d.).

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