AP Bio Digestion System (Kfogler)

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Credit: Kim Fogler

Animal Nutrition

AP Biology 2006-2007
What do animals need to live?
 Animals make energy
using:
 food food
 oxygen

 Animals build bodies


using: ATP
 food for raw materials O
2
 amino acids, sugars,
fats, nucleotides
 ATP energy for synthesis
AP Biology
Nutritional requirements
 Animals are heterotrophs
 need to take in food
 Why? fulfills 3 needs…

 fuel = chemical energy for production of ATP


 raw materials = carbon source for synthesis
 essential nutrients = animals cannot make
 elements (N, P, K, Fe, Na, K, Ca...), NAD, FAD, etc.

AP Biology
How do animals get their food?

filter (suspension) feeding substrate feeding

AP Biology
fluid feeding bulk feeding
AP Biology
Different diets; different lives
 All animals eat other organisms
 Herbivores
 eat mainly plants
 gorillas, cows,
rabbits, snails
 Carnivores
 eat other animals
 sharks, hawks, spiders, snakes
 Omnivores
 eat animals & plants
 cockroaches, bears, raccoons, humans
 humans evolved as hunters, scavengers & gatherers
AP Biology
AP Biology
Getting & Using Food
 Ingest
 taking in food
 Digest
 mechanical digestion
 breaking up food into smaller pieces
intracellular
 chemical digestion digestion
 breaking down food into molecules
small enough to be absorbed into cells
 enzymes (hydrolysis)
 Absorb
 absorb across cell membrane
 diffusion
 active transport
 Eliminate
 undigested extracellular material
extracellular
AP Biology passes out of digestive system digestion
Digestive systems
Everybody’s got one!

AP Biology
Human digestive system
Alimentary Canal

AP Biology
Common processes & structures
 Movement & Control
 peristalsis
 push food along by rhythmic waves of
smooth muscle contraction in walls of
digestive system
 sphincters
 muscular ring-like valves, regulate the
passage of material between sections of
digestive system
 Accessory glands
 salivary glands, pancreas, liver & gall
bladder
 secrete digestive juices (enzymes & fluid)
AP Biology
Swallowing (& not choking)

 Epiglottis
 problem: breathe & swallow through same orifice
 flap of cartilage
 closes trachea (windpipe) when swallowing
 food travels down esophagus
 Esophagus
 move
AP Biology food along to stomach by peristalsis
Ingestion
 Mouth
 mechanical digestion
 teeth
 breaking up food
 chemical digestion
 saliva
 amylase
 enzyme digests starch
 mucin
 slippery protein (mucus)

 protects soft lining of digestive system

 lubricates food for easier swallowing

 buffers
 neutralizes acid to prevent tooth decay

 anti-bacterial chemicals
 kill bacteria that enter mouth with food
AP Biology
mouth
break up food
moisten food
digest starch
kill germs

AP Biology
Ooooooh!
Stomach Zymogen!

Functions
 food storage
 can stretch to fit ~2L food
 disinfect food
 HCl = pH 2
 kills bacteria
 breaks apart cells
 chemical digestion
 pepsin
 enzyme breaks down proteins
 secreted as pepsinogen
 activated by HCl

But the stomach is made out of protein!


What stops the stomach from digesting itself?
mucus secreted by stomach cells protects
AP Biology
stomach lining
mouth stomach
break up food kills germs
moisten food store food
digest starch break up food
kill germs digest proteins

cardiac
sphincter

pyloric
sphincter

AP Biology
Coevolution of parasite & host
Ulcers Colonized by Free of
H. pylori
H. pylori
 Used to think
ulcers were
caused by stress inflammation of
stomach
inflammation of
esophagus
 tried to control with
antacids
H. pylori
 Now know ulcers
caused by
bacterial inflammatory
proteins
cell damaging
proteins
(VacA)
infection of (CagA)

stomach
 Helicobacter pylori cytokines
helper T cells
 now cure with
neutrophil cells
antibiotics white blood cells

AP Biology
1982 | 2005
Revolutionizing healthcare
"for their discovery of the bacterium Helicobacter pylori and its role
in gastritis and peptic ulcer disease"

Helicobacter pylori
J. Robin Warren

Barry Marshall
AP Biology
Small intestine
 Function
 major organ of digestion & absorption
 chemical digestion
 digestive enzymes
 absorption through lining
 over 6 meters!
 small intestine has huge surface area = 300m2 (~size
of tennis court)

 Structure
 3 sections
 duodenum = most digestion
 jejunum = absorption of nutrients & water
 ileum = absorption of nutrients & water
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Duodenum
 1st section of small intestines
 acid food from stomach mixes with
digestive juices from accessory glands:
 pancreas
 liver
 gall bladder

AP Biology
What stops
Ooooooh!
pancreas
fromZymogen !
Pancreas digesting
itself
 Digestive enzymes
 peptidases
 trypsin
 trypsinogen
 chymotrypsin small intestines
 chimotrypsinogen
 carboxypeptidase
 procarboxypeptidase
 pancreatic amylase
 Buffers
 reduces acidity
 alkaline solution rich in
bicarbonate (HCO3-) Explain
Explain how
how this
this is
is aa
 buffers acidity of material from molecular
molecular example
example of of
AP Biology stomach structure-function
structure-function theme.
theme.
mouth stomach
break up food kills germs
moisten food break up food
digest starch digest proteins
kill germs store food

pancreas
produces enzymes to
digest proteins & starch

AP Biology
Liver
 Digestive System Functions
 produces bile
 stored in gallbladder until needed
 breaks up fats
 act like detergents to breakup fats

Circulatory System
Connection
bile contains
colors from old
red blood cells
collected in liver =
iron
iron in
in RBC
RBC rusts
rusts &
&
AP Biology
makes feces
makes feces brown
brown
mouth stomach
break up food kills germs
moisten food break up food
digest starch digest proteins
kill germs store food
liver
produces bile
- stored in gall
bladder
break up fats

pancreas
produces enzymes to
digest proteins & starch

AP Biology
Digestive enzymes

AP Biology
Absorption by Small Intestines
 Absorption through villi & microvilli
 finger-like projections
 increase surface area for absorption

Ooooh…
Structure-Function
theme!

AP Biology
Absorption of Nutrients
 Passive transport
 fructose
 Active (protein pumps) transport
 pump amino acids, vitamins & glucose
 against concentration gradients across
intestinal cell membranes
 allows intestine to absorb much higher
proportion of nutrients in the intestine than
would be possible with passive diffusion
 worth the cost of ATP!
nutrients are valuable…
AP Biology grab all you can get!
mouth stomach
break up food kills germs
moisten food break up food
digest starch digest proteins
kill germs store food
liver
produces bile
- stored in gall
bladder
break up fats small intestines
breakdown all foods
pancreas - proteins
produces enzymes to - starch
digest proteins & starch - fats
- nucleic acids
absorb nutrients

AP Biology
Large intestines (colon)
 Function
 re-absorb water
 use ~9 liters of water every
day in digestive juices
 > 90% of water reabsorbed
 not enough water absorbed
back to body
 diarrhea

 too much water absorbed back to body


 constipation

AP Biology
You’ve got
company!
Flora of large intestines
 Living in the large intestine is a rich
flora of harmless, helpful bacteria
 Escherichia coli (E. coli)
 a favorite research organism
 bacteria produce vitamins
 vitamin K; biotin, folic acid & other B vitamins
 generate gases
 by-product of bacterial
metabolism
 methane, hydrogen sulfide

AP Biology
Rectum
 Last section of colon (large intestines)
 eliminate feces
 undigested materials
Tell them  extracellular waste
about the rabbits,  mainly cellulose from plants
George!
 roughage or fiber
 salts
 masses of
bacteria
appendix
AP Biology
mouth stomach
break up food kills germs
moisten food break up food
digest starch digest proteins
kill germs store food
liver
produces bile
- stored in gall
bladder
break up fats small intestines
breakdown food
pancreas - proteins
produces enzymes to - starch
digest proteins & carbs - fats
absorb nutrients

large intestines
AP Biology absorb water
Appendix
Vestigial organ

AP Biology
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AP Biology 2006-2007

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