012-Trichuris Trichiura and Enterobius

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Trichuris trichiura Trichuriasis

hair tail
♂ ♀
3cm 4cm

Ingestion of contaminated
green vegetables with
Whip-like embryonated Trichuris egg
Geographical Distribution: cosmopolitan
Definitive host: Man Rhabditiform
Habitat: caecum & adjacent parts larva
Infective stage
Embryonated egg
Geohelminthic infection
Develop on the ground Diagnostic stage
Egg in stool
Diagnostic Stage Infective Stage

Embryonated egg
S 50X25 µ Egg containing
Barrel-shaped rhabditiform larva
S Thick-shelled
Mucoid plug‫د مخاطى‬77‫س‬ Mode of Infection
at each pole
C brownish Ingestion of embryonated
egg in contaminated food
C Immature ovum or drink
Pathogenesis and Clinical Picture
Inflammation & irritation of the mucosa with
haemorrhages. Submucosal abscesses & ulcers.
Mild infection: asymptomatic

Moderate infection: nausea, vomiting,


bloody diarrhoea & lower abdominal pain.

Heavy infection (complications):


1- Dysentery:
Anterior part of worms embedded
in intestinal mucosa cause
oedematous, hyperaemic, fragile
mucosa. Stool with mucus and
blood.
2- Perforation

Peritonitis

3- Invasion of appendix

Appendicitis
Blood loss
Microcytic hypochromic
4- Anaemia anaemia
Due to Toxic byproducts of the worm
Macrocytic hyperchromic
5- Eosinophilia anaemia

6- Rectal prolapse

Normal rectum Rectal prolapse


Anal tone Anal tone is lost Patient with rectal prolapse
is present due to infection showing Trichuris worms
Diagnosis
1- Stool analysis
to detect eggs

2- Rectal examination
by proctoscopy
‫منظار شرجى‬

3- Air-contrast barium enema.


4- Blood examination: anaemia and eosinophilia

Treatment Epidemiology and control


Albendazole As in Ascaris
Enterobius vermicularis Enterobiasis
intestine live worm
Called: pin worm ‫لدودة‬77‫ا‬
‫دبوسية‬‫ل‬77‫ا‬
Geographical Distribution: cosmopolitan.
Definitive host: man only
Habitat: caecum and adjacent parts.
Diagnostic stage: egg
S: 50 X 20 µ

S: plano-convex Plane Convex
♀ 5 mm
10 mm long
has 2 layers long
covered with outer sticky
albuminous layer Eggs are found mainly on
C: translucent perianal skin.
C: rhabditiform larva
Mode of infection in Enterobiasis

Female
migrates
during
♀ night

Ingestion of eggs by:
Autoinfection (hand to mouth)
Contaminated food or drink
Handling contaminated linen,
clothing and articles.
Rhabditiform larva
Air-born in dust
Retro-infection Eggs are infective in few hours
Pathogenesis and Clinical Picture

• Sticky egg laid in the perianal


region at night causes
Pruritus ani.

• Pruritus ani leads to


nervous irritability, hyperactivity
and insomnia (‫لليل‬77‫ا‬777‫)أرقب‬
Pathogenesis and Clinical Picture
• Female worms may migrate to ectopic sites stimulates:
Granuloma formation
Fallopian
tube

Peritoneal
uterus cavity
vagina
urethra
appendix
Urinary infection Appendicitis Vulva-vaginitis
(Involuntary micturition) Intestine Pelvic peritonitis
‫لالإرادى‬77‫لتبولا‬77‫ا‬ diarrhoea & abdominal pain
Secondary enuresis
Diagnosis
Clinically: pruritus ani at night.

Laboratory:
- Swabbing of perianal area to detect
the eggs by: NIH swab Cellophane

NIH swab
Scotch adhesive tape
- Adults may be seen in stool
or anal area.

- Eggs are rarely found in stool


Treatment
 Albendazole.

 It should be repeated after 2 weeks.

 All members of the family should be simultaneously


‫وقت‬
( ‫ل‬77‫فسا‬77‫ىن‬777‫ )ف‬treated.

 Application of white mercury oxide (white


precipitate ointment) around the anus at night.
Relieves itching, kills female worms coming out of
the anus and prevents dispersal 7‫بعثر‬777‫ ت‬of eggs.
Epidemiology
• Eggs become mature and infective in few hours.
• Pruritus leads to autoinfection.
• Prevalent in Egypt
(common in children and old age)

Prevention and Control


• Mass treatment.
• Personal hygiene and food protection.
• Infected children should use tightly fitting trousers
at night.
Short Question
Appendicitis is a common clinical presentation facing Surgeons.
 Enumerate four helminthic infections that may be accompanied
by appendicitis.
Ascaris lumbricoides Trichuris trichiura
infection. infection.

Enterobius vermicularis Taenia saginata


infection. infection.

 Choose one that commonly affects children.


How can you treatAlbendazole
this in both infections
infection?
Enterobius vermicularis infection Drug is repeated (2 w later)
Ascaris lumbricoides infection Drug is given to all family
Treated first in mixed infection
Case
A young boy was playing with his friends a football
match. Suddenly he felt acute abdominal pain. His
mother took him to the doctor. The condition was
diagnosed as a case of acute appendicitis.
a- What are the probable parasites that may cause this condition?
Taenia Trichuris Enterobius Ascaris
b- If the mother gave a history that her child had eaten green
salad, what will be the probable parasite that has caused this
condition?
Ascaris Trichuris Enterobius
c- How can you confirm your diagnosis?
Stool analysis to detect of characteristic eggs
Performing peri-anal swab for detection of Enterobius eggs

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