Difficult Dogs IVAPM
Difficult Dogs IVAPM
Difficult Dogs IVAPM
DIFFICULT
DOGS
General Rules of Thumb
(How to Keep Your Thumbs)
Ability to decline patients
Muzzled before arrival if dangerous
Set aside adequate time
Charge for your time
Safety First!
Health of pet vs. intact vet
Liability (owner injury)
Liability (patient injury)
Adequate staff
Adequate equipment
Adequate drugs
Oral Sedation
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ult_dogs.htm
Usually inadequate (easily overridden)
False sense of security
Keep your health insurance up-to-date if
using this method routinely
Oral Sedation (continued)
Acepromazine: 0.5-2.0 mg/kg
Diazepam: 1.0-2.0 mg/kg (disinhibition)
Alprazolam: 0.1-0.5 mg/kg (disinhibition)
Combinations:
Telazol 10-20 mg/kg w/ Acepromazine 2
mg/kg: given in a “meatball” at home;
profound sedation, long recovery
Oral Sedation (continued)
Acepromazine 1-2 mg/kg w/ Diazepam 0.5-
1.0 mg/kg
Phenobarbital 2.5 mg/kg w/ Diazepam 0.5-
1.0 mg/kg
Injectable Sedation
Better when combinations of drugs are
used
Opioids form the basis of most
combinations (neuroleptanalgesia)
Unless anesthetized, any dog can bite
Unless anesthetized, any dog can bite
Opioids– Which one and why?
Nalbuphine: 0.4 mg/kg; very inexpensive,
not controlled, variable sedation
Butorphanol: 0.2 mg/kg; moderately
expensive, C IV, mild to moderate sedation
Buprenorphine: 0.010-0.020 mg/kg;
expensive, C III, usually not recommended
due to minimal sedative qualities
Opioids (continued)
Mu agonists– very inexpensive, C II, more
side effects (bradycardia, vomiting, etc.)
Morphine: 0.5-1.0 mg/kg IM (if used IV, give
very slowly to minimize histamine release)
Hydromorphone: 0.1-0.2 mg/kg IM, IV
Fentanyl: 0.005-0.010 mg/kg IM, IV
Medetomidine/Opioid (Domitor)
Profound sedation, good analgesia
Rare catecholamine override
Moderately expensive
Side effects include bradycardia, initial
hypertension
Avoid if cardiac disease, organ failure
Add anticholinergic if brachycephalic or
vagal stimulation anticipated
Medetomidine/Opioid (cont.)
Medetomidine dose: 0.005-0.040 mg/kg IM
or IV (low end if IV)
Increasing dose increases duration and
degree of sedation
Can add induction agent (watch doses!) if
sedation insufficient
Reversible with atipamezole (Antisedan)
Acepromazine/Opioid
Variable sedation (usually good)
Side effects include hypotension,
hypothermia, rare collapse (Boxers)
Very inexpensive
Reasonably safe with cardiac disease
(caution with forward failure)
Acepromazine dose: 0.01-0.1 mg/kg IM, IV
Long duration, irreversible
Benzodiazepine/Opioid
Midazolam preferred for IM use
Variable sedation (better in geriatric or
compromised patients)
Fewest CV effects
Variable expense (midazolam>diazepam)
Benzo dose: 0.1-0.4 mg/kg IM, IV
Short duration; reversible with flumazenil
Telazol (tiletamine/zolazepam)
Dissociative/benzodiazepine (anesthetic)
Can be used alone (better with opioid)
Expensive; minimal analgesia alone
Short duration anesthesia, long, rough
recovery (tiletamine>zolazepam duration)
Caution with CV, organ disease
5-10 mg/kg IM; 2-5 mg/kg IV
SUMMARY