Introduction KA-1
Introduction KA-1
of Analytical Chemistry
Chemical Analysis and
Analytical Chemistry
Chemical analysis:
Includes any aspect of the chemical
characterization of a sample material
Analytical Chemistry:
“ Science of chemical measurements”
Area of Chemical Analysis and
The Questions
Identification
What is the identity of the substance in the sample?
Detection
Does the sample contains substance X?
Quantitation
How much of substance X is in the sample?
Separation
How can the species of interest be separated from the
sample matrix for better quantitation and identification?
What is Analytical Chemistry?
Analytical chemistry provides the methods and the tools
needed for insight into our material world for answering
four questions about material sample:
1. What?
2. Where?
3. How much?
4. What arrangement, structure or form?
(Fresenius’ J. Anal. Chem. 343 (1992) 812 - 813
The Role of Analytical Chemistry
Analytical chemists work to improve the reliability of
existing techniques to meet the demands for better
chemical measurements which arise constantly in our
society
They adapt proven methodologies to new kinds of
materials or to answer new questions about their
composition
They carry out research to discover completely new
principles of measurements and are at the forefront of the
utilization of major discoveries such as lasers and
microchip devices for practical purposes.
Analytical Chemistry Applied to:
Chemistry
Medicine (hospital)
Oceanography
Forensic Science
Farming
Environmental Science
Biology
Geology (geological survey)
Material Science
Archeology
Food Science
History of Analytical Methods
Classical methods:
early years (separation of analytes) via precipitation,
extraction or distillation
Qualitative:
recognized by color, boiling point, solubility, taste
Quantitative:
gravimetric or titrimetric measurements
Instrumental methods:
newer, faster, more efficient
Physical properties of analytes:
conductivity, electrode potential, light emission absorption,
mass to charge ratio and fluorescence, many more..
Analyte
What is it (chemical analysis) Qualitative analysis
How much is it present? Quantitative analysis
Analyte
the species being measured in chemical analysis (chemical
substance)