Special Considerations: Resuscitation of Premature Babies

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Special considerations

Resuscitation of premature babies


Ethics and Care at End of Life
Special considerations
 Situations that may complicate
resuscitation and cause ongoing problem
 Post-resuscitation management
 Resuscitation outside hospital or beyond
time of birth
Difficult situations
 Not able to ventilate adequately
 Cyanosis despite adequate ventilation
 Bradycardia despite adequate ventilation
 No spontaneous breathing despite
adequate ventilation
Not able to ventilate
 Mechanical blockage of airways
 Meconium or mucus in pharynx or trachea
Tracheal suction
 Choanal atresia
Pass small-caliber suction catheter, oral airway
 Pharyngeal malformation (Robin syndrome)
Prone, nasopharyngeal airway
 Other rare conditions (laryngeal web)
Emergency tracheostomy
Not able to ventilate
 Impaired lung functions
 Pneumothorax
Diminished air entry, transillumination, X-ray, drain
 Congenital pleural effusion
Hydrops, Drain
 Congenital diaphragmatic hernia
Intubate, orogastric tube
 Pulmonary hypoplasia
 Extreme prematurity High inflation pressure
 Congenital pneumonia
Cyanosis/Bradycardia despite
adequate ventilation

 Cyanotic heart disease


 Congenital heart block

Ensure adequate ventilation


No spontaneous breathing despite
adequate ventilation
 Brain injury (HIE, severe acidosis,
congenital neuromuscular disorder)
 Sedation due to drugs given to mother
(narcotic drugs, magnesium sulfate,
general anesthesia, non-narcotic
analgesics)
Naloxone
 Indications
 Continued respiratory depression after PPV
has restored a normal heart rate and color
AND
 History of maternal narcotic administration
within past 4 hours
Naloxone
 Recommended concentration = 1.0 mg/ml
 Route: IV preferred; IM acceptable but
delayed onset of action; ET not
recommended
 Dose: 0.1 mg/kg
 May require repeated administration
Post-resuscitation care
 Temperature control
 Close monitoring of vital signs
 Laboratory studies
Post-resuscitation care
 Look for complications
 Pulmonary hypertension
 Pneumonia/other lung complications
 Metabolic acidosis
 Hypotension
 Seizures
 Apnea
 Hypoglycemia
 Feeding problem
Resuscitation outside hospital or
beyond time of birth
 Same principles (Restore adequate
ventilation)
 Alternative heat source (Skin-to-skin contact)
 Clear airway (Bulb syringe, wipe with a cloth)
 Ventilation (Mouth-to-mouth-and-nose)
 Vascular access (Peripheral vein
cannulation/intraosseus needle)
Resuscitation and Prematurity
 Thin skin, large surface area and ↓ fat
 Oxygen toxicity
 Weak muscles - difficulty in breathing
 Immature nervous system –less respiratory
drive
 Immature lung
 Fragile brain capillaries
 Small blood volume
Additional Resources Needed
 Additional trained personnel
 Additional means of maintaining temperature
 Re closable, food grade polyethylene bag
 Portable warming pad
 Transport incubator

 Additional means to control oxygenation


(in a hospital in which babies at <32 weeks gestation are born electively)
 Compressed air source
 Oxygen blender
 Pulse oximeter
Keeping a premature baby warm
 Increase temperature of the delivery room
 Pre-heat the radiant warmer
 Pre- warmed transport incubator
Keeping a premature baby warm
 If baby is born at less
than 28 weeks
gestation, consider
placing him below the
neck in a re closable
polyethylene bag
without first drying the
skin
 Avoid overheating
Oxygen in a premature baby
 Connect a blender to compressed oxygen and
air sources and to PPV device
 Start somewhere between room air and 100%
oxygen
 Attach a pulse oximeter to baby’s foot or hand
 Heart rate displayed by pulse oximeter should
agree with heart rate that you palpate or hear
Oxygen in a premature baby
 Adjust oxygen concentration to achieve an
oxygen saturation that gradually increases
to 90%
 Accept 70% to 80% if-heart rate is
increasing and oxygen saturation is
increasing
 If saturation is less than 85% and not
increasing, increase oxygen concentration
 Decrease oxygen concentration of
saturation rises above 95%
Oxygen in a premature baby

!
Resuscitation efforts not to be
delayed while waiting for pulse
oximeter to display a strong
signal
Ventilation in a premature baby
 Consider giving CPAP if the baby Is breathing
spontaneously and has a heart rate above 100
bpm but has
 Labored breathing or
 Is cyanotic or
 Has low oxygen saturation

 By using flow-inflating bag or T-piece


resuscitator
CPAP
Ventilation in a premature baby
 Use lowest inflation pressure necessary to
achieve adequate response
 Initial inflation pressure of 20-25 cm H2O
 May need higher pressure if no
improvement in heart rate and no chest
rise
Ventilation in a premature baby
 Prophylactic surfactant as per your
practice

! Baby should be fully


resuscitated before surfactant
is given
How to decrease chances of brain
injury in a premature baby?
 Gentle handling
 No head-down position
 Avoid excessive positive pressure or CPAP
 Adjust ventilation and oxygen concentration
gradually and appropriately (use pulse
oximeter and blood gas)
 Do not give rapid infusion of fluids
 Avoid infusion of hypertonic solutions
Post-resuscitation management of
a premature baby
 Monitor blood sugar
 Monitor for apnea and bradycardia
 Give and adjust ventilation and oxygen
concentration gradually and appropriately
 Give feeding slowly and cautiously
 Increase suspicion of infection
Ethics and neonatal resuscitation

 Primary role in determining goals of care


with parents
 Informed consent based on complete and
reliable information (may not be available
before or immediately after delivery)
Not to initiate resuscitation
 Confirmed gestational age of less than 23
weeks or birth weight less than 400 gm
 Anencephaly
 Confirmed trisomy 13 or 18
 If parents wish: confirmed gestational age
of 24-25 weeks

Based on your survival rates and local policy


Counseling parents before a high
risk birth
 Obstetrician and neonatologist perspectives
may be different
 Short and long term outcome of babies of
different gestation in your hospital
 Discuss resuscitation and level of care to
be given to baby
 Documentation
When to stop resuscitation?
 No heart rate after 10 minutes of complete
and adequate resuscitation
 No evidence of other causes of
compromise

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