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    Beta Nanoparticles

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    wafa nagi
    This document discusses the use of nanoparticles in nanomedicine. It outlines how nanoparticles can be used for drug delivery by encapsulating drugs in magnetic nanoparticles, nanocomposite hydrogels, or attaching them to "smart drugs" targeting specific antigens. Nanoparticles like carbon nanotubes, gold nanoparticles, and silicon nanowires can also be used for disease detection by attaching antibodies to identify cancer cells or viruses. Molecular imaging is another application where quantum dots or gold nanoparticles are used to track movement of molecules or angiogenesis. Some concerns regarding the toxicity of nanoparticles on living organisms are also mentioned.

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    © All Rights Reserved
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    Beta Nanoparticles

    Uploaded by

    wafa nagi
    63 views15 pages
    This document discusses the use of nanoparticles in nanomedicine. It outlines how nanoparticles can be used for drug delivery by encapsulating drugs in magnetic nanoparticles, nanocomposite hydrogels, or attaching them to "smart drugs" targeting specific antigens. Nanoparticles like carbon nanotubes, gold nanoparticles, and silicon nanowires can also be used for disease detection by attaching antibodies to identify cancer cells or viruses. Molecular imaging is another application where quantum dots or gold nanoparticles are used to track movement of molecules or angiogenesis. Some concerns regarding the toxicity of nanoparticles on living organisms are also mentioned.

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    Beta_Nanoparticles.ppt

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    This document discusses the use of nanoparticles in nanomedicine. It outlines how nanoparticles can be used for drug delivery by encapsulating drugs in magnetic nanoparticles, nanocomposite hydrogels, or attaching them to "smart drugs" targeting specific antigens. Nanoparticles like carbon nanotubes, gold nanoparticles, and silicon nanowires can also be used for disease detection by attaching antibodies to identify cancer cells or viruses. Molecular imaging is another application where quantum dots or gold nanoparticles are used to track movement of molecules or angiogenesis. Some concerns regarding the toxicity of nanoparticles on living organisms are also mentioned.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    63 views15 pages

    Beta Nanoparticles

    Uploaded by

    wafa nagi
    This document discusses the use of nanoparticles in nanomedicine. It outlines how nanoparticles can be used for drug delivery by encapsulating drugs in magnetic nanoparticles, nanocomposite hydrogels, or attaching them to "smart drugs" targeting specific antigens. Nanoparticles like carbon nanotubes, gold nanoparticles, and silicon nanowires can also be used for disease detection by attaching antibodies to identify cancer cells or viruses. Molecular imaging is another application where quantum dots or gold nanoparticles are used to track movement of molecules or angiogenesis. Some concerns regarding the toxicity of nanoparticles on living organisms are also mentioned.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    of 15

    Nanoparticles and their medical

    applications

    By:
    Maryam Liaqat
    Jason Feng
    Eric Ma
    Outline

     Nanomedicine – what is it?

     Nanoparticle Applications:
    – Drug Delivery - Maryam
    – Detection - Eric
    – Imaging - Jason

     Nanotechnology Concerns
    Nanomedicine

     Nanotechnology applied medically


     New breakthroughs in medicine
    – Advanced biomedical research tools
    – Labels to experiments
    – Study of DNA and its component genes
    – Diagnostic tests
    – In bone implants etc…
    Drug Delivery Methods

     Systems that deliver drugs to specific sites

     Sample Methods:
    – Smart Drugs

    – Nanocomposite hydrogel systems

    – Magnetic Nanoparticles
    Drug Delivery

     Smart drugs
    – Attack specific antigens
    – Immunotoxins that are protein in nature
    – Consist of an antibody part and toxic part
    Drug Delivery

     Nanocomposite hydrogel systems


    – Thermo therapeutic process
    – Releases drugs that are encapsulated on heating
    – Gold nanoshells/nanoparticles can be used
    – Ideal wavelengths of light are infra red i.e 800-1200nm
    Drug Delivery

     Magnetic Nanoparticles
    – Drugs are bound to magnetic nanoparticles
    – Carry drugs to malignant sites with magnetic fields
    – Release the drugs by enzymatic activity
    Disease Detection

     Cancer/Virus Detection
    – Carbon Nanotubes
    – Gold nanoparticles & Nanodots
    – Nanowires
     Gene Detection
    – Silicon nanowires

    Picture taken from


    http://mednews.wustl.edu/tips/page/normal/5036.html
    Cancer/Virus Detection
     Carbon Nanotubes:
    – Covered with monoclonal antibodies
    – Antibodies for growth factor receptor commonly found in
    cancer cells
    – Current increases measured
     Silicon Nanowires
    – Similar in use to nanotubes
    – Antibodies attached to wire Taken from http://www.news.harvard.edu/gazette/
    – Current changes measured 2004/10.07/01-nanovirus.html

    – Can be applied to cancer cells and viruses


    Cancer/Virus Detection

     Gold Nanoparticles & Nanodots


    – Similar application
    – Antibodies attached to nanoparticles
    – Nanoparticle antibodies bind to cancer cells
    – Colors reflected when light hits particles
    – Shapes and sizes affect color

    Taken from http://www.gatech.edu/news-room


    /release.php?id=561
    Gene Detection

     Silicon nanowire:
    – Can detect specific genes
    – Nucleic acids attached to nanowires
    – Specific sequences can be created
    – Sensor capable of differentiating mutated and
    nonmutated genes
    – PCR not needed -> detection time lowered
    Imaging Techniques

     Conventional Techniques:
    – X-ray, MRI, Fluoroscopy
    – CAT scan
     Limitations
    – Limited detail
    – Difficult to track movement
    Taken from: http://www.besttreatments.co.uk/btuk
    /images/lung_cancer_xray.jpg
    Imaging Applications

     Molecular Tracking:
    – Use Quantum Dots as labels
     Dots attached to molecules before injection
    – Fluoroscopy used to track movement
     Colors from dots seen and imaged
    Imaging Applications

     Tracking blood flow:


    – Tag proteins of cells with gold nanoparticles
    – View process of angiogenesis
     Important for cancer detection and imaging
     Cancer Imaging:
    – Injection of gold nanoparticles
    – Localization around tumors
    – CT scan shows cancerous regions Taken from http://www.rsna.org/
    Publications/rsnanews/oct05/nanoparticles.cfm
    Possible Concerns

     Negative biological side-effects:


    – Toxicity of quantum nanodots
    – Effects on living organisms not well known
     Gold nanoparticles safer:
    – Biologically inert
    – Won’t interact with other chemicals

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