SNH Tambahan

Download as pptx, pdf, or txt
Download as pptx, pdf, or txt
You are on page 1of 13

Blood pressure, ischemic stroke, and

thrombolysis
• BP goal of <185/110 mm Hg
• In cases where such a target is not achieved, tPA may even be
withheld, given the association of elevated BP and risk of sICH
leading to poor clinical outcomes.
• A proficient attempt must be made to reduce BP to the
thrombolytic range, even if it involves using multiple BP agents or
continuous infusions.
• Keeping in mind the importance of not making the patient
relatively hypotensive, the safety of aggressively lowering BP to
<185/110 mm Hg
• As discussed, the need for rapid BP control in both
AIS and ICH often requires IV agents.
• Some of the commonly used IV medications are
nicardipine, labetalol, sodium nitroprusside,
nitroglycerine, enalaprilat, and hydralazine.
BP and ischemic stroke when
thrombolysis is not an option
• As a result, it is best to observe current guidelines, which
recommend a 15% reduction within the first 24 hours of
ischemic stroke only in cases where BP exceeds 220/120 mm Hg.
• Patients with acute ischaemic stroke and a BP lower than
180/105 mmHg in the first 72 hours after stroke do not seem to
benefit from the introduction or reintroduction of BP-lowering
medication. For stable patients who remain hypertensive
(≥140/90 mmHg) more than three days after an acute ischaemic
stroke, initiation or reintroduction of BP-lowering medication
should be considered. Restarting BP control is reasonable after
the first 24 hours for hypertensive patients who are stable.
• For ICH patients presenting with SBP between 150
and 220 mmHg and without contraindication to
acute BP treatment, acute lowering of SBP to 140
mmHg is safe and can be effective for improving
functional outcome.
• For ICH patients presenting with SBP >220 mmHg, it
may be reasonable to consider aggressive reduction
of BP with a continuous intravenous infusion and
frequent BP monitoring.
• Patients with cerebellar hemorrhage who are deteriorating neurologically or who have
brainstem compression and/or hydrocephalus from ventricular obstruction should
undergo surgical removal of the hemorrhage as soon as possible. Initial treatment of
these patients with ventricular drainage rather than surgical evacuation is not
recommended (Class III; Level of Evidence C). (Unchanged from the previous guideline)
• 2. For most patients with supratentorial ICH, the usefulness of surgery is not well
established. Specific exceptions and potential subgroup considerations are outlined
below in recommendations 3 through 6.
• 3. A policy of early hematoma evacuation is not clearly beneficial compared with
hematoma evacuation when patients deteriorate
• 4. Supratentorial hematoma evacuation in deteriorating patients might be considered as
a life-saving measure
• 5. DC with or without hematoma evacuation might reduce mortality for patients with
supratentorial ICH who are in a coma, have large hematomas with significant midline
shift, or have elevated ICP refractory to medical management
• 6. The effectiveness of minimally invasive clot evacuation with stereotactic or endoscopic
aspiration with or without thrombolytic usage is uncertain
• https://www.slideshare.net/HelaoSilas/hemorrhagi
c-stroke-66379385

You might also like