Carbohydrate Metabolism - MCQs 2

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The passage discusses topics related to metabolism including the TCA cycle, lipogenesis, gluconeogenesis, and Wernicke-Korsakoff psychosis.

Gluconeogenesis involves the conversion of pyruvate to glucose through steps like pyruvate carboxylation, phosphoenolpyruvate formation from oxaloacetate, and glucose formation from fructose-1,6-bisphosphate.

Acetyl-CoA gets converted to glucose.

1.

Which among the following intermediates of


TCA cycle participates in the biosynthesis of
Heme?

A. Oxaloacetate
B. Fumarate
C. Succinyl CoA
D. Citrate
2. Fructose feeding increases lipogenesis
because it

A. activates acetyl CoA carboxylase


B. bypasses the PFK control point
C. increases insulin secretion
D. decreases serum free fatty acid levels
3.Impaired oxidation of Fatty Acids gives rise to
hypoglycemia because of the following EXCEPT

A. Sparing effect Fatty acid oxidation on the non-


obligatory oxidation of glucose
B. Acetyl CoA gets converted to glucose
C. Acetyl-CoA activates pyruvate carboxylase
D. NADH and ATP are required for gluconeogenesis
4. Wernicke-Korsakoff psychosis is related to the
following EXCEPT:
A. It is also known as cerebral beriberi
B. Chronic alcoholics as vulnerable to develop
C. Decreased conversion of Pyruvate to
Acetyl CoA
D. Deficiency of Niacin
5. The following tissues require continuous
supply of glucose supported by
gluconeogenesis even under resting
conditions EXCEPT:
A. Skeletal muscle
B. Brain
C. RBCs
D. Lens of the eye
6. Which among the following key
gluconeogenic enzymes is involved in the
reversal of Pyruvate kinase step of Glycolysis?

A. Pyruvate carboxylase
B. Phosphofructokinase 2
C. Fructose 1,6-bisphosphatase
D. Glucose 6 phosphatase
7. Utilization of glycerol for gluconeogenesis
under fasting conditions is related to the
following EXCEPT
A. Glycerol kinase is absent in adipose tissue
B. Glycerol phosphate dehydrogenase is
essential
C. Insulin enhances the activity of hormone
sensitive lipase in the adipose tissue
D. Under fasting conditions Insulin / Glucagon

ratio decreases
8. The HMP shunt pathway is characterized by the
following EXCEPT

A. Takes place in the mitochondrion


B. There is no production of ATP
C. There is production of CO2
D. Uses NADP+ as coenzyme
9. Which among the following inhibits
gluconeogenesis?

A. Acetyl CoA
B. Citrate
C. AMP
D. Glucagon
10. Insulin increases synthesis of the following in
liver EXCEPT?

A. Ketone bodies
B. Protein
C. Glycogen
D. Fatty acid
Feed back
For each of the following statements, please
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B. I thought this was a boring activity

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E. I had the choice of participating in this activity

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G. I feel open book exam is more beneficial as a
revision exercise than self study

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exercise like open book examination

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directed learning process

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learning during open book exam
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M. I prefer MCQs than short answer questions in the


conduct of open book exams

N. Different sets of MCQs in the open book and pre/post


tests are more beneficial in the learning process

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