Bipolar Disorder - Tebe

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Journal Reading

BIPOLAR DISORDER
Diagnosis and Treatment of Bipolar Disorders in A
dults: A Review of The Evidence on Pharmacologic
Treatments

Tubagus Arif Hidayatullah


201720401011148

Mentor: dr. Iwan Sys I., SpKJ

Department of Psychiatry
Faculty of Medicine Universitas Muhammadiyah Malang
2019
DEFINITION
Bipolar disorder is a chronic,
relapsing illness characterized by with intervening periods that are
relatively (but not fully) symptom-free
recurrent episodes of manic or .
depressive symptoms,
EPIDEMIOLOGY
The lifetime prevalence
of bipolar disorder in adults in the 3,9 %
United States is reported
DIAGNOSIS
This Disorder has 2 major types:
BP I is defined by episodes of
depression and the presence of
mania
BP II is characterized by episodes
of depression and hypomania.
Severe mania cause functional
impairment, include psychosis.
While hypomania is not severe
enough to cause impairment in
social or occupational functioning
Patients with bipolar disorder of
either type experience symptomatic
depression 3 times more frequently
than symptomatic mania or
hypomanic
Patients screening for history of
mania and hypomania on their initial
depressive symptoms is the initial
recognition of bipolar disorder.
The examiner could use instrument to
validate such as Mood Disorder
Questionnaire, the Composite
International Diagnostic Interview,
and the Primary Care Evaluation of
Mental Disorders Patient Health
Questionnaire
TREATMENT
Pharmacological

• Mood Stabilizer
Pharmacological treatment
Lithium has been the
for bipolar disorder include
foundation of treatment, but
the conventional mood it’s efficacy in prevent and
stabilizer and most of treatment of depression is
atypical antipsychotics limited, while for acute mania
is not rapidly effective
Pharmacological

• Atypical Antipsychotic
Sodium valproate is the most
The most established role for
frequently used antiepileptic
this class is in the treatment
mood stabilizer for patients with
of acute mania, all approved
bipolar disorder.
atypical antipsychotic have
been shown to be effective.
Notes

1 Patients with bipolar disorder are predisposed to other comorbid psychiatric


disorders at higher rates than patients with other psychiatric disorders

2 Suicide among patients with bipolar disorder is estimated to occur at


an annual rate of 0.4%

3 Women of childbearing age comprise a special population requiring vigilance b


y caregivers and healthcare providers, with the risk of recurrence episodes
Thank You

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