Journal Reading: Tuberculosis
Journal Reading: Tuberculosis
Journal Reading: Tuberculosis
TUBERCULOSIS
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Tuberculosis (TB) continues to be one of the greatest challenges
to global health. In 2015, 10.4 million people were estimated to
have developed TB and 1.4 million died of the disease.
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Risk factors for progressive primary disease include
immunosuppression (especially HIV infection), extremes of age,
or a large inoculation of mycobacteria. However, in most infected
individuals, TB remains clinically and microbiologically latent for
many years. This condition, known as latent TB infection, may be
detectable only by a positive tuberculin skin test or interferon γ
release assay result, or by the presence of radiologically
identifiable calcification at the site of primary lung infection or in
regional lymph nodes.
Jeong YJ, Lee KS, Yim JJ, Jeong YJ, Lee KS, Yim JJ. The diagnosis of
pulmonary tuberculosis: a Korean perspective. Precision and Future
Medicine. 2017 Jun 30;1(2):77-87. 8
Chest radiographs play an important role in the screening and
diagnosis of pulmonary TB. The typical radiographic findings of
pulmonary TB in immunocompetent hosts consist of focal or
patchy heterogeneous consolidation involving the apical and
posterior segments of upper lobes and the superior segments of
lower lobes (Fig. 2)
Jeong YJ, Lee KS, Yim JJ, Jeong YJ, Lee KS, Yim JJ. The diagnosis of
pulmonary tuberculosis: a Korean perspective. Precision and Future
Medicine. 2017 Jun 30;1(2):77-87. 9
Another common finding includes
poorly defined nodules and linear
opacities. Single or multiple
cavities are radiographically
evident in 20% to 45% of patients
Jeong YJ, Lee KS, Yim JJ, Jeong YJ, Lee KS, Yim JJ. The diagnosis of
pulmonary tuberculosis: a Korean perspective. Precision and Future
Medicine. 2017 Jun 30;1(2):77-87. 10
However, radiographs may be normal or show only mild or
nonspecific findings in patients with active disease. Actually,
initial radiographic diagnoses of TB are correct in only 49% of
cases.
Jeong YJ, Lee KS, Yim JJ, Jeong YJ, Lee KS, Yim JJ. The diagnosis of
pulmonary tuberculosis: a Korean perspective. Precision and Future
Medicine. 2017 Jun 30;1(2):77-87. 11
In immunocompromised hosts, pulmonary TB manifests as
miliary TB, hilar or mediastinal lymphadenopathy, and pleural
effusion on chest radiographs (Fig. 3)
Jeong YJ, Lee KS, Yim JJ, Jeong YJ, Lee KS, Yim JJ. The diagnosis of
pulmonary tuberculosis: a Korean perspective. Precision and Future
Medicine. 2017 Jun 30;1(2):77-87. 12
Jeong YJ, Lee KS, Yim JJ, Jeong YJ, Lee KS, Yim JJ. The diagnosis of
pulmonary tuberculosis: a Korean perspective. Precision and Future
Medicine. 2017 Jun 30;1(2):77-87. 13
CT is more sensitive than chest radiography for the detection
and characterization of subtle parenchymal disease and
mediastinal lymphadenopathy. With CT, a diagnosis of
pulmonary TB is correct in 91% of patients and TB is correctly
excluded in 76% of patients
For example, in one study of 41 patients with active TB, CT
whereas chest radiographs
depicted cavities in 58%,
showed cavities in only 22%.
Jeong YJ, Lee KS, Yim JJ, Jeong YJ, Lee KS, Yim JJ. The diagnosis of
pulmonary tuberculosis: a Korean perspective. Precision and Future
Medicine. 2017 Jun 30;1(2):77-87. 14
Table 1 summarizes the characteristic CT findings of
parenchymal, lymph node, airway, and pleural TB.
Jeong YJ, Lee KS, Yim JJ, Jeong YJ, Lee KS, Yim JJ. The diagnosis of
pulmonary tuberculosis: a Korean perspective. Precision and Future
Medicine. 2017 Jun 30;1(2):77-87. 15
Jeong YJ, Lee KS, Yim JJ, Jeong YJ, Lee KS, Yim JJ. The diagnosis of
pulmonary tuberculosis: a Korean perspective. Precision and Future
Medicine. 2017 Jun 30;1(2):77-87. 16
Jeong YJ, Lee KS, Yim JJ, Jeong YJ, Lee KS, Yim JJ. The diagnosis of
pulmonary tuberculosis: a Korean perspective. Precision and Future
Medicine. 2017 Jun 30;1(2):77-87. 17
TB remains a global health concern. Accurate and rapid diagnosis
of TB and the determination of drug resistance using bacterial,
molecular, and radiographic evaluations are critical for adequate
treatment and for protecting communities.
Jeong YJ, Lee KS, Yim JJ, Jeong YJ, Lee KS, Yim JJ. The diagnosis of
pulmonary tuberculosis: a Korean perspective. Precision and Future
Medicine. 2017 Jun 30;1(2):77-87. 18
JOURNAL READING
ATELECTASIS
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2 major causes of an opacified hemithorax:
• Atelectasis of entire lung
• very large pleural effusion
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In obstruction atelectasis, the visceral and parietal pleura almost
never separate each other mobile structures in the thorax are
pulled toward the side of the atelectasis producing a shift
toward the side of opafication
Atelectasis can be classified either by its pathophysiology or by the
region and extent of lung involved
These cases include lobar atelectasis and complete lung collapse
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LOBAR ATELECTASIS
RIGHT UPPER LOBE ATELECTASIS
COMPLETE LUNG ATELECTASIS
COMPLETE LUNG ATELECTASIS
REFERENCES
1. García EB, Sanz CA, Morena AM, Valcarcel PQ, Aldehuela CA,
Sancho CI. Radiological signs of lobar collapse, Chest
radiographic findings and CT imaging correlation. Europian
Society of Radiology. 2011; C-1379
2. Herring W. Learning Radiology Recognizing The Basics. 3rd
Edition: Elsevier, 2015
PNEUMONIA
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PNEUMONIA
Community Acquired Pneumonia
Kesan : Bronkopneumonia
Kesan : Pneumonia
Imaging findings of CAP are varied and often nonspecific. However, some characteristic findings
are sometimes suggestive of specific pathogens. In addition, imaging examinations, especially CT,
can offer clues to the differentiation between infectious pneumonia and noninfectious diseases.
To accomplish this differentiation, familiarity with imaging characteristics of CAP as well as those
of noninfectious diseases is indispensable.
REFERENSI