Esophagitis: Prepared By: SIEGA, Devorah O. BSN-3

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ESOPHAGITIS

Prepared By: SIEGA,


Devorah O.
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DEFINITION

Esophagitis is inflammation that may


damage tissues of the esophagus,
the muscular tube that delivers food
from your mouth to your stomach.
Esophagitis can cause painful,
difficult swallowing and chest pain.
Causes of esophagitis include
stomach acids backing up into the
esophagus, infection, oral
medications and allergies.
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Treatment for esophagitis depends
on the underlying cause and the
severity of
tissue damage. If left untreated,
esophagitis can damage the lining of
the esophagus and interfere with its
normal function, which is to move
food and liquid from your mouth to
your stomach. Esophagitis can also
lead to complications such as
scarring or narrowing of the
esophagus, and difficulty
swallowing.
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SIGNS & SYMPTOMS

Common sings and symptoms


of esophagitis include:
• Difficult swallowing
• Painful swallowing
• Chest pain, particularly behind
the breastbone, that occurs
with eating
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• Heartburn
• Acid regurgitation
In young children, signs of
symptoms may include:
• Feeding difficulties
• Failure to thrive

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CAUSES

Esophagitis is generally categorized


by the condition that cause it. In
some cases, more than one factor
may be causing esophagitis.
• Reflux esophagitis
• Eosinophilic esophagitis
•Drug-induced esopghagitis
• Infectious esophagitis
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TESTS AND DIAGNOSIS

• Barium X-ray
• Endoscopy
• Laboratory tests

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TREATMENTS AND DRUGS

• Reflux esophagitis
-Over the counter treatments
-Prescription strength medications
-Surgery
• Eosinophilic esophagitis
- Proton pump inhibitors

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- Topical swallowed steroids
- 6 food elimination diet
• Drug induced esophagitis
- Treatment for drug induced
esophagitis is primarily avoiding the
problem drug when possible and
reducing the risk with better pill
taking habits
• Infectious esophagitis
- A medication to treat a bacterial,
viral, fungal, or parasitic infection
causing infectious esophagitis.
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LIFESTYLE AND HOME
REMEDIES

Depending on the type of


esophagitis you have, you may
lessen symptoms or avoid recurring
problems by following these steps.
1.Avoid foods that may increase
reflux
2.Use good pill taking habits
3.Lose weight
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4. If you smoke, quit.
5. Avoid certain medications

6. Avoid stooping or bending


7. Avoid lying down after
eating
8. Raise the head of your bed.

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Esophagitis pathophysiology
Overview
The esophagus is a part of the
gastrointestinal tract which is responsible
of moving the food from the mouth to the
rectum.
Esophagitis is defined as inflammation of
mucosal layer of esophagus. Based on the
etiology of inflammation esophagitis can
be classified into reflux esophagitis and
eosinophilic esophagitis. Any condition
that lead to the reflux of the gastric acidic
contents into the esophagus results in
reflux esophagitis.
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Eosinophilic esophagitis is an immunoallergic
disorder resulting from the interaction
between genetics and environmental triggers
such as repeated exposure to food and
aeroallergens.
TH2 inflammatory cell response play a major
role in the production of eosinophils. Activated
TH2 response leads to the recruitment and
activation of eosinophils and mast cells.
Characteristic gross pathology findings of
esophagitis include fixed esophageal ring,
white exudates, longitudinal furrows/ fibrosis,
mucosal pallor, Diffuse esophageal narrowing.

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Characteristic microscopic findings
of esophagitis include edema and
basal hyperplasia (non-specific
inflammatory changes), lymphocytic
infiltration, neutrophilic infiltration,
eosinophilic infiltration, goblet cell
intestinal metaplasia or Barrett's
esophagus and elongation of the
papillae.

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