Principles of Inheritance: "The Child Is The Father of The Man"
Gregor Mendel conducted experiments with pea plants to study inheritance of traits from parents to offspring. He discovered that traits are controlled by discrete factors, now known as genes, and that these genes segregate and assort independently during the formation of gametes. Mendel established that inheritance follows two laws: 1) the law of segregation, where alleles separate during gamete formation, and 2) the law of independent assortment, where alleles assort independently of each other. Through his work, Mendel laid the foundation for modern genetics.
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Principles of Inheritance: "The Child Is The Father of The Man"
Gregor Mendel conducted experiments with pea plants to study inheritance of traits from parents to offspring. He discovered that traits are controlled by discrete factors, now known as genes, and that these genes segregate and assort independently during the formation of gametes. Mendel established that inheritance follows two laws: 1) the law of segregation, where alleles separate during gamete formation, and 2) the law of independent assortment, where alleles assort independently of each other. Through his work, Mendel laid the foundation for modern genetics.
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PRINCIPLES OF
INHERITANCE
“THE CHILD IS THE
FATHER OF THE MAN” Who do you look like? Your mother or your father?
If your father is good
in math, what is the probability that you are also good at it? GREGOR MENDEL AND HIS EXPERIMENTS ON PEAS • Gregor mendel Austrian monk • Peas can self fertilize (can you do that too?) • (what do you think would be the traits of offspring of self fertilization compared to the parent? ) • Trait any characteristic that can be passed from parents to offspring • Pure bred vs hybrid • Gene using mendel’s idea, is the factor that controls trait • Dominant trait inherited trait that manifested in an organism • Recessive trait inherited trait that did not manifest in an organism MENDEL’S HYPOTHESES • Each trait is controlled by something called a “factor” within the organization • Many factors have two or more forms • One form of each factor is dominant over the other • Each organism has two factors for each trait, one from the mother and one from the father • Each of the two factors separate when gametes form • Gametes of individual contain only one factor for each trait • During fertilization, the single factors are united to make a pair in the offspring • The two factors do not blend MENDEL’S LAWS ON INHERITANCE • Law of segregation each pair of alleles segregate or separates during meiosis. Allele two gene copies of the same trait • Law of independent assortment gene pairs segregate into gametes randomly and independently of each other GENETIC TERMINOLOGIES • Big letter = for dominant allele; small letter = for recessive allele • Genotype the actual genetic makeup of an organism • Phenotype the form of the trait that is observed or that is manifested, in an organism • Homozygous (for a particular trait) an organism that has two identical alleles for that particular trait. • Example = pure bred • Heterozygous organism that has two non-identical alleles for a trait • Example = hybrid WHY DO PLANTS OF THE SAME SPECIE LOOK VERY SIMILAR WHILE ANIMALS DO NOT? HYBRIDS • Monohybrid crosses a cross which considers only one trait at a time • Dihybrid crosses a cross which considers the inheritance of two traits at a time • Testcross • Is done to determine whether the individual is heterozygous or homozygous for a certain trait • Individual with unknown genotype is bred to an individual with recessive trait. • If ½ of offspring show recessive phenotype, the parent is heterozygous. If all offspring show dominant phenotype = parent is homozygous • Intermediate inheritance incomplete dominance, codominance, multiple allele, and polygenic inheritance • Incomplete dominance heterozygote shows a phenotype that is intermediate between two homozygous phenotypes (looks blend) • Codominance both alleles in the heterozygote express themselves fully • Multiple alleles means there are three or more alleles for a trait in the population • Polygenic trait trait that is controlled by two or more gene pairs • Pleiotropy ability of a single gene to have multiple effects • Penetrance proportion of individuals who show phenotype that is expected from their genotype • Expressivity the degree to which a particular gene is expressed in individuals showing the trait