Endometriosis is a benign gynecological condition where endometrial tissue grows outside the uterus, most commonly causing pelvic pain, painful periods, and infertility. It has various proposed etiologies and is diagnosed through medical history, clinical examination, imaging like ultrasound and CT, and laparoscopy. Treatment involves medication like hormonal contraceptives, progestins, anti-progestins, and GnRH analogs or surgery like laparoscopy, with the goal of relieving symptoms and restoring fertility.
Endometriosis is a benign gynecological condition where endometrial tissue grows outside the uterus, most commonly causing pelvic pain, painful periods, and infertility. It has various proposed etiologies and is diagnosed through medical history, clinical examination, imaging like ultrasound and CT, and laparoscopy. Treatment involves medication like hormonal contraceptives, progestins, anti-progestins, and GnRH analogs or surgery like laparoscopy, with the goal of relieving symptoms and restoring fertility.
Endometriosis is a benign gynecological condition where endometrial tissue grows outside the uterus, most commonly causing pelvic pain, painful periods, and infertility. It has various proposed etiologies and is diagnosed through medical history, clinical examination, imaging like ultrasound and CT, and laparoscopy. Treatment involves medication like hormonal contraceptives, progestins, anti-progestins, and GnRH analogs or surgery like laparoscopy, with the goal of relieving symptoms and restoring fertility.
Endometriosis is a benign gynecological condition where endometrial tissue grows outside the uterus, most commonly causing pelvic pain, painful periods, and infertility. It has various proposed etiologies and is diagnosed through medical history, clinical examination, imaging like ultrasound and CT, and laparoscopy. Treatment involves medication like hormonal contraceptives, progestins, anti-progestins, and GnRH analogs or surgery like laparoscopy, with the goal of relieving symptoms and restoring fertility.
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ENDOMETRIOSIS
Dr. Andi Mardiah Tahir, SpOG
Divisi Fertilitas Endokrinologi Reproduksi (FER) Bag. OBGIN FK UNHAS Pandangan Umum
Endometriosis penyk jinak
ginek, > usia reprod jar endom berada diluar kav.uteri Kausa ??? sangat dipengaruhi hormon steroid (E) Erat hub (80%) Nyeri pelvik, nyeri haid & infertilitas ETIOLOGI (Disease of the theories)
Regurgitasi & Implantasi haid
(Simpson,1927) Genetik & Imunologi (Dmowski) Metaplasia (Meier) Induksi darah haid Fc lingk di C.D / cairan peritn aktifitas angiotensin m Fc lingk :merkuri,DTT/Dioxin Diagnosis
Anamnesis: nyeri pelvik (70-
80%),nyeri organ-2 Infertil: 70-80% pd unexpl.infert Pem klinis : nyeri & nodul-2 Pem penunjang : USG, CT scan CA 125. Unt D/ pasti Laparoskopi Stadium-2 (AFS & EEC) Unt pengobatan & eval hsl R/ AFS :4 stad i. Minimal (lesi min pd perit &1ov) ii.Mild (lesi pd perit, ke2 ov, C.D) iii.Moderate (perit, tuba, ke2 ov & perlengketan minimal-sedang) iv.Severe (perit, tuba, ke2 ov, C.D. & perlengketan luas) EEC : stqa kec pd stad.4:pd organ diluar rgg pelvik (usus,paru,dll) Terapi
Prinsip : R/ secepat mungkin
Medikamentosa :pil KB, progest, anti prog, mifepriston,GnRh analog(agonis/antag),aromatase inhibitor. Pembedahan / Laparoskopi Kombinasi Bl ES + : Add back therapy ADENOMIOSIS
Endometriosis dlm miometrium
nyeri haid & infertilitas Rekurensi tinggi Respon jelek dg GnRh analog Diagnosis : Anamnesis USG Laparoskopi MRI Manajemen & Prognosis