RBC Membrane
RBC Membrane
RBC Membrane
Alick Mwambungu
Red cell membrane
The primary function of the red cell is the
transport of respiratory gases to and from
the tissues.
MEMBRANE CARBOHYDRATES
Membrane Lipids
Lipid components of the red cell
membrane are:
30% free unesterified cholesterol.
10% Glycerides and free fatty
acids.
60% Phospholipids
Membrane Phospholipids
Amino phospholipids-Phosphatidyl
ethanolamine and phosphatidyl serine are
restricted to the cytoplasmic layer.
Membrane Cholesterol
Membrane Proteins
These are either:
-Peripheral or
-Integral
Membrane Proteins
Ankyrin(Bands 2.1-2.3)
This serves to anchor assembled spectrin
molecules to the lipid bilayer.
Accomplished by binding simultaneously
to the spectrin tetramers and to the
interior domain of the integral protein-
Band3
Red Cell Membrane Proteins
Actin(Band 5)
It is a globular protein
Composed of filaments
The filaments bind weakly to the tail end
of both α and β spectrins.
Red Cell Membrane proteins
Band 4.1
It’s a globular protein
Integral Proteins