Scribd Logo
Upload

Welcome to Scribd!

  • 482 views

    Limfadenopati

    Uploaded by

    Namira Syafitri
    Lymphadenopathy refers to swollen or enlarged lymph nodes. It can be caused by infection, autoimmune disease, or malignancy. Localized lymphadenopathy is due to a localized infection near the swollen lymph nodes, while generalized lymphadenopathy involves swelling of lymph nodes all over the body, often due to a widespread infection. Enlarged lymph nodes are a common symptom of many infectious diseases like bacterial or viral infections as well as some cancers. The causes can be reactive, tumoral, of autoimmune etiology, or of unknown origin.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd

    Limfadenopati

    Uploaded by

    Namira Syafitri
    482 views3 pages
    Lymphadenopathy refers to swollen or enlarged lymph nodes. It can be caused by infection, autoimmune disease, or malignancy. Localized lymphadenopathy is due to a localized infection near the swollen lymph nodes, while generalized lymphadenopathy involves swelling of lymph nodes all over the body, often due to a widespread infection. Enlarged lymph nodes are a common symptom of many infectious diseases like bacterial or viral infections as well as some cancers. The causes can be reactive, tumoral, of autoimmune etiology, or of unknown origin.

    Original Title

    limfadenopati

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    DOC, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Lymphadenopathy refers to swollen or enlarged lymph nodes. It can be caused by infection, autoimmune disease, or malignancy. Localized lymphadenopathy is due to a localized infection near the swollen lymph nodes, while generalized lymphadenopathy involves swelling of lymph nodes all over the body, often due to a widespread infection. Enlarged lymph nodes are a common symptom of many infectious diseases like bacterial or viral infections as well as some cancers. The causes can be reactive, tumoral, of autoimmune etiology, or of unknown origin.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    482 views3 pages

    Limfadenopati

    Uploaded by

    Namira Syafitri
    Lymphadenopathy refers to swollen or enlarged lymph nodes. It can be caused by infection, autoimmune disease, or malignancy. Localized lymphadenopathy is due to a localized infection near the swollen lymph nodes, while generalized lymphadenopathy involves swelling of lymph nodes all over the body, often due to a widespread infection. Enlarged lymph nodes are a common symptom of many infectious diseases like bacterial or viral infections as well as some cancers. The causes can be reactive, tumoral, of autoimmune etiology, or of unknown origin.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    of 3

    Lymphadenopathy is a term meaning "disease of the lymph nodes.

    "[1] It is, however, almost synonymously used with "swollen/enlarged lymph nodes". It could be due to infection, autoimmune disease, or malignancy. Inflammation of a lymph node is called lymphadenitis.[2] In practice, the distinction between lymphadenopathy and lymphadenitis is rarely made. (Inflammation of lymph channels is called lymphangitis.[3])

    Localized lymphadenopathy : due to localized spot of infection e.g. an infected spot on the scalp will cause lymph nodes in the neck on that same side to swell up Generalized lymphadenopathy : due to generalized infection all over the body e.g. influenza o persistent generalized lymphadenopathy (PGL) : persisting for a long time, possibly without an apparent cause Dermatopathic lymphadenopathy : lymphadenopathy associated with skin disease.

    Tangier disease (ABCA1 deficiency) may also cause this Cause Enlarged lymph nodes are a common symptom in a number of infectious and malignant diseases. It is a recognized symptom of many diseases, of which some are as follows:

    Reactive: acute infection (e.g. bacterial, or viral), or chronic infections (tuberculous lymphadenitis, cat-scratch disease). o The most distinctive symptom of bubonic plague is extreme swelling of one or more lymph nodes that bulge out of the skin as "buboes." The buboes often become necrotic and may even rupture. o Infectious mononucleosis is an acute viral infection, the hallmark of which is marked enlargement of the cervical lymph nodes. o It is also a symptom of cutaneous anthrax, measles and Human African trypanosomiasis, the latter two giving lymphadenopathy in lymph nodes in the neck. o Toxoplasmosis, a parasitic disease, gives a generalized lymphadenopathy (Piringer-Kuchinka lymphadenopathy).[4] o Plasma cell variant of Castleman's disease - associated with HHV-8 infection and HIV infection. o Mesenteric lymphadenitis after viral systemic infection (particularly in the GALT in the appendix) can commonly present like appendicitis. Tumoral: o Primary: Hodgkin lymphoma and non-Hodgkin lymphoma give lymphadenopathy in all or a few lymph nodes. [4] o Secondary: metastasis, Virchow's Node, Neuroblastoma, and Chronic Lymphocytic Leukemia. Autoimmune etiology: systemic lupus erythematosus, rheumatoid arthritis all giving a generalized lymphadenopathy.[4] Immunocompromised etiology: AIDS. Generalized lymphadenopathy is an early sign of infection with human immunodeficiency virus (HIV), the virus that causes acquired immunodeficiency syndrome (AIDS). "Lymphadenopathy syndrome" has been used to describe the first symptomatic stage of HIV progression, preceding a diagnosis of AIDS.[5] Bites from certain venomous snakes, most notably the black mamba, kraits, Australian brown snakes, coral snakes, tiger snakes, taipans, death adders, and some of the more toxic species of cobra. Unknown etiology: Kikuchi disease, progressive transformation of germinal centres, sarcoidosis, hyaline-vascular variant of Castleman's disease, Rosai-Dorfman disease, Kawasaki disease Benign (reactive) lymphadenopathy

    There are three distinct patterns of benign lymphadenopathy:


    Follicular hyperplasia - Seen in infections, autoimmune disorders, and nonspecific reactions. Paracortical hyperplasia - Seen in viral infections, skin diseases, and nonspecific reactions.

    Sinus histiocytosis - Seen in lymph nodes draining limbs, inflammatory lesions, and malignancies.

    You might also like