DIVISION OF GEN.

TRIAS CITY
Project ISuLAT Activity Sheets in Science
(Intensified Support to Learning Alternatives Through Modules and Worksheets)

Science 8 - Quarter 4 _ Week 2

Name: ____________________________________________ Grade/Section: ___________________

Teacher: __________________________________________ Score: ____________________________

Activity Sheet No. 2 - MELC 21-22: Comparing the processes of

Mitosis and Meiosis and their role in the division cycle

START UP
At the end of this worksheet, the learners will be able to:
1. describe the cell cycle
2. compare the processes of mitosis and meiosis in cell division
3. explain the significance of meiosis in maintaining the chromosome number

Every living thing undergoes reproduction. The nutrients taken by any individual
will provide for energy for metabolic processes, growth and development as well as
reproduction. The cellular level of reproduction, in the form of cell division, provides the
backdrop for the organismal level of reproduction.

CAPTURE

● Cell Cycle-the cell undergoes a cycle of a very short period of cell division and a
longer growing and resting period.

⮚ Interphase –a stage of a cell cycle wherein the cell is in its resting place.
This is the time when the cell grows, gets nutrients and conducts a normal
cell function. The interphase is divided into 3 sub stages:

1. First gap period or 𝐺1 –a period of cell growth and cellular contents

duplication. RNA (ribonucleic acid) and protein synthesis also happens
in this period.
2. Synthesis (S) period- a period in which DNA is synthesized and
replicated.
3. Second gap period or 𝐺2 - a period when the cell double checks the
duplicated chromosomes and makes some corrections, a period of
preparation before the cell enters the mitosis stage.

● During the interphase stage the nucleus is visible with a nuclear membrane.
Nucleolus is still visible and chromatin materials appear as thin like structures
disappeared in the nucleus.

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 DIVISION OF GEN. TRIAS CITY
Project ISuLAT Activity Sheets in Science
(Intensified Support to Learning Alternatives Through Modules and Worksheets)

Cell’s life cycle

onlinebiologynotes.com

● Cell Division- alternating with the interphase is the cell division phase. In
eukaryotic cells there are two types of cell division: mitosis and meiosis.

Stages of Mitosis
This type of cell division produces two identical cells with the same number
of chromosomes (Diploid cell). Mitosis happens in the body cells or somatic cells.
It is divided into 4 stages.
1. Prophase- chromatin condenses into chromosomes. Mitosis happens in the
body cell or somatic cell. Each chromosome is composed of sister
chromatids joined together by a structure called centromere. At this stage
the nuclear envelope breaks down and a pair of microtubules called
centriole appears near the nucleus.

2. Metaphase- Chromosomes align at equatorial plates and are held in place

in place by a microtubule attached to spindle fiber.

3. Anaphase- Centromere divides and sister chromatids separate and move

towards the opposite poles.

4. Telophase- Daughter chromosomes arrive at the poles and microtubules

disappear. The nuclear envelope reappears and cytoplasm divides forming
invaginations and eventually producing two daughter cells.

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 DIVISION OF GEN. TRIAS CITY
Project ISuLAT Activity Sheets in Science
(Intensified Support to Learning Alternatives Through Modules and Worksheets)

Stages of Mitosis
https://teaching.ncl.ac.uk/bms/wiki/index.php/File:MITOSI
S

Stages of Meiosis
● Meiosis- It takes place in plants and animals whenever gametes or sex cells are
formed through the process of gametogenesis. Meiosis is a special type of cell
division where the cell undergoes two rounds of cell division to produce four
daughter cells, each with half the chromosome number as the original parent cell
and with a unique set of genetic material as a result of exchange of chromosome
segments during the process of crossing over and chromosome number is reduced
to half (haploid cell).
● Sexually reproducing organisms undergo meiosis to produce haploid gametes in
preparation for sexual reproduction.
● Meiosis plays an important role in maintaining the chromosome number. In this
process the chromosome number is reduced into half so that when the gametes
cells (egg and sperm) unite, upon fertilization the chromosome number normally
remains the same with the species. It does not double or triple for every generation
because any alteration in the process may result in species genetic disorder.
● This process happens in the sex cells or gamete cells.
● The first round of meiotic division, also known as Meiosis I, consists of Four
Stages: Prophase I, Metaphase I, Anaphase I, and Telophase I.
1. STAGES OF MEIOSIS I
a. Prophase I- chromosomes begin to pair and crossing-over takes place
where a segment of a sister chromatid of one chromosome is exchanged
with the same segment of the sister chromatid of the homologous
chromosome through the formation of a cross-linkage of the segment
called chiasma. After crossing over, the sister chromatids are no longer
similar with each other based on the genes they contain.
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 DIVISION OF GEN. TRIAS CITY
Project ISuLAT Activity Sheets in Science
(Intensified Support to Learning Alternatives Through Modules and Worksheets)

b. Metaphase I- tetrads line up along the equator of the spindle. Spindle

fibers attach to the centromere region of each homologous chromosome
pair.
c. Anaphase I- the tetrads separate and are drawn to opposite poles by the
spindle fibers. The centromeres remain intact.
d. Telophase I- similar to telophase of mitosis except that only one set of
replicated chromosomes in each cell. Telophase I is followed by
Interphase II. At this time each chromosome still has two sister
chromatids and is still undergoing another round of division.

2. Meiosis II
● Meiosis II – referred to as the second meiotic division is similar with
mitosis stages. This includes Prophase II, Metaphase II, Anaphase II
and Telophase II. This process will result in four cells, two from each
daughter cell from meiosis I, with one half the diploid chromosome
numbers and with only one sister chromatid for each chromosome.

Stages of Meiosis in Squash Anther

teachmephysiology.com

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 DIVISION OF GEN. TRIAS CITY
Project ISuLAT Activity Sheets in Science
(Intensified Support to Learning Alternatives Through Modules and Worksheets)

INTEGRATE

Learning Task No. 1. Complete the diagram of the stages of the cell cycle by selecting
the description on the given boxes below.

Learning Task No. 2. Compare mitosis and meiosis by completing the table.

Basis of Comparison MITOSIS MEIOSIS

Number of daughter cell produced

Number of chromosomes is halved. (Yes/No)

Pairing of homologous chromosomes takes place.
(Yes/No)
The daughter cells produced are always identical in
terms of genetic material. (Yes/No)
Type of cell undergoing the process.

Learning Task No. 3

1. Why is mitosis important in an organism?
_______________________________________________________________________________
_______________________________________________________________________________
2. What is the role of meiosis in sexual reproduction?
_______________________________________________________________________________
_______________________________________________________________________________

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 DIVISION OF GEN. TRIAS CITY
Project ISuLAT Activity Sheets in Science
(Intensified Support to Learning Alternatives Through Modules and Worksheets)

ENRICH

Construct a concept map on the difference between meiosis and mitosis using the given
descriptions below.

Criteria 5 4 3 2
Shows better Shows good Shows fair Shows poor
1. Content understanding understanding understanding understanding
of mitosis and of mitosis and of mitosis and of mitosis and
meiosis. meiosis. meiosis. meiosis.
Illustration is Illustration Illustration
2. Clarity Illustration
easy to somehow hardly makes
makes sense.
understand. makes sense. sense.
Shows Shows fair Shows little Shows poor
3. Creativity expressiveness expressiveness expressiveness expressiveness
of imagination.of imagination. of imagination. of imagination.
good concept poorly
4. Organization well organized map
fairly organized
organized
concept map concept map
organization concept map
Highest Possible Score: 20 Lowest Possible Score: 8

References:
Jauco, Magdalena C. et.al., (2018) General Science and Technology Innovations
and Beyond 8, pages 288-293
Science 8 Learner’s Module, pages 317-328

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