Deepseek
Deepseek
Dicalcium phosphate (DCP, CaHPO₄·2H₂O) is an inorganic phosphate supplement widely used in animal
nutrition to correct phosphorus (P) and calcium (Ca) deficiencies. It is a highly bioavailable source of
these minerals, playing a critical role in bone development, energy metabolism, and cellular functions
(McDowell, 2003). In dairy cattle, phosphorus is particularly vital for optimal reproductive performance,
as it influences ovarian function, estrus cyclicity, and fertility (DeLuca, 2004). Repeat Breeding Syndrome
(RBS), a condition characterized by failure to conceive after multiple inseminations in otherwise healthy
cows, is often linked to mineral imbalances, particularly phosphorus deficiency (Prabhakar et al., 2015).
This review explores the significance of DCP supplementation in dairy cattle, focusing on its role in
improving reproductive efficiency, recommended dosage, and its therapeutic potential in managing RBS.
DCP is a preferred mineral supplement due to its high solubility, stability, and balanced Ca:P ratio
(approximately 1.3:1). The National Research Council (NRC, 2001) recommends a dietary phosphorus
level of 0.30–0.40% of dry matter (DM) for lactating dairy cows. However, in phosphorus-deficient
regions or high-yielding dairy herds, supplementation with DCP at 30–50 g/day is commonly practiced to
meet metabolic demands (Underwood & Suttle, 1999).
Phosphorus is a key component of adenosine triphosphate (ATP), nucleic acids, and cell membranes,
making it essential for reproductive processes such as:
Uterine involution and embryo survival – Adequate P levels support uterine contractility and
endometrial health (Sordillo, 2016).
Hormonal regulation – Phosphorus influences the secretion of luteinizing hormone (LH) and
progesterone, both critical for maintaining pregnancy (Weiss, 2017).
Repeat breeder cows often suffer from subclinical phosphorus deficiency, necessitating targeted
supplementation. Research suggests that:
50–70 g/day of DCP for 30–60 days pre- and post-insemination improves conception rates
by 15–20% (Prakash & Madan, 2014).
Combined supplementation with vitamin D₃ and magnesium enhances P absorption and
utilization (Goff, 2018).
Blood phosphorus levels should be maintained at 4.5–6.0 mg/dL for optimal fertility (Radostits
et al., 2007).
1. Restoring Phosphorus Balance – Corrects subclinical deficiencies that impair ovarian function.
3. Reducing Oxidative Stress – Phosphorus is a cofactor for antioxidant enzymes like glutathione
peroxidase (Sordillo, 2016).
Conclusion
Dicalcium phosphate is a vital mineral supplement in dairy cattle nutrition, particularly for improving
fertility in repeat breeder cows. Strategic supplementation at 50–70 g/day can significantly enhance
conception rates by addressing phosphorus-related metabolic and reproductive dysfunctions. Further
research should explore the interaction between DCP, trace minerals, and hormonal profiles in RBS-
affected herds.
References
Goff, J. P. (2018). The role of phosphorus in lactation and reproduction. Journal of Dairy Science,
101(5), 4283-4292.
Khan, Z. U., et al. (2012). Impact of phosphorus on fertility in dairy cattle. Theriogenology, 78(3),
485-494.
Prabhakar, S., et al. (2015). Mineral deficiencies and repeat breeding in dairy cows. Veterinary
World, 8(5), 623-628.
Radostits, O. M., et al. (2007). Veterinary Medicine: A Textbook of the Diseases of Cattle, Sheep,
Pigs, Goats, and Horses. Saunders.
Sordillo, L. M. (2016). Nutritional strategies to optimize dairy cattle immunity. Journal of Dairy
Science, 99(6), 4967-4982.
Underwood, E. J., & Suttle, N. F. (1999). The Mineral Nutrition of Livestock. CABI Publishing.
This review synthesizes current knowledge on DCP’s role in dairy cattle reproduction, providing a
scientific basis for its therapeutic use in RBS management. Future studies should investigate long-term
effects and optimal formulation strategies for maximal fertility enhancement.