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    Tamoxifen Nolvadex

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    Adrianne Bazo
    Tamoxifen is prescribed to treat breast cancer by competing with estrogen for binding sites and reducing estrogen response. It is taken orally once daily as 20mg. Common side effects include nausea and hot flashes. Nursing implications focus on monitoring for liver and thyroid function changes, as well as hypercalcemia in patients with bone metastases. The patient should be instructed to take tamoxifen as directed and report any bone pain or other side effects to their healthcare provider.

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    Tamoxifen Nolvadex

    Uploaded by

    Adrianne Bazo
    881 views1 page
    Tamoxifen is prescribed to treat breast cancer by competing with estrogen for binding sites and reducing estrogen response. It is taken orally once daily as 20mg. Common side effects include nausea and hot flashes. Nursing implications focus on monitoring for liver and thyroid function changes, as well as hypercalcemia in patients with bone metastases. The patient should be instructed to take tamoxifen as directed and report any bone pain or other side effects to their healthcare provider.

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    Tamoxifen is prescribed to treat breast cancer by competing with estrogen for binding sites and reducing estrogen response. It is taken orally once daily as 20mg. Common side effects include nausea and hot flashes. Nursing implications focus on monitoring for liver and thyroid function changes, as well as hypercalcemia in patients with bone metastases. The patient should be instructed to take tamoxifen as directed and report any bone pain or other side effects to their healthcare provider.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    881 views1 page

    Tamoxifen Nolvadex

    Uploaded by

    Adrianne Bazo
    Tamoxifen is prescribed to treat breast cancer by competing with estrogen for binding sites and reducing estrogen response. It is taken orally once daily as 20mg. Common side effects include nausea and hot flashes. Nursing implications focus on monitoring for liver and thyroid function changes, as well as hypercalcemia in patients with bone metastases. The patient should be instructed to take tamoxifen as directed and report any bone pain or other side effects to their healthcare provider.

    Copyright:

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    Adrianne Bazo

    11-18-08

    Clinical Medications Worksheets


    Generic Name Trade Name Classification Dose Route Time/frequency
    tamoxifen Nolvadex Antineoplastics/ 20mg PO Q day
    antiestrogens
    Peak Onset Duration Normal dosage range
    Several months 4-10wk Several weeks 10-20 mg twice daily; doses of 20 mg/day may be taken as a single
    dose
    Why is your patient getting this medication For IV meds, compatibility with IV drips and/or
    Adjuvant therapy of breast cancer after surgery and radiation solutions
    (delays recurrence) NA

    Mechanism of action and indications Nursing Implications (what to focus on)


    (Why med ordered) Contraindications/warnings/interactions
    Competes with estrogen for binding sites in breast and other Hypersensitivity. Do not crush, break, chew, or administer an
    tissues antacid within 1-2 hr of enteric-coated tablet.
    Reduces DNA synthesis and estrogen response Common side effects
    Nausea, hot flashes

    Interactions with other patient drugs, OTC or Lab value alterations caused by medicine
    herbal medicines (ask patient specifically) Monitor CBC, platelets, and calcium levels before and during therapy.
    None for this pt May cause transient hypercalcemia in patients with metastases to the
    bone. An estrogen receptor assay should be assessed before initiation
    of therapy. Monitor serum cholesterol and triglyceride concentrations
    in patients with pre-existing hyperlipidemia. May cause ↑
    concentrations. Monitor hepatic function tests and thyroxine (T4)
    periodically during therapy. May cause ↑ serum hepatic enzyme and
    thyroxine concentrations.
    Gynecologic examinations should be performed regularly; may cause
    variations in Papanicolaou and vaginal smears
    Be sure to teach the patient the following about this
    medication
    Instruct patient to take medication as directed. If a dose is missed, it
    should be omitted. Advise patient to report bone pain to health care
    professional promptly. This pain may be severe. Inform patient that this
    may be an indication of the drug's effectiveness and will resolve over
    time. Analgesics should be ordered to control pain. monitor weight
    weekly. Weight gain or peripheral edema should be reported to health
    care professional
    Nursing Process- Assessment Assessment Evaluation
    (Pre-administration assessment) Why would you hold or not give this Check after giving
    Assess for an increase in bone or tumor pain. med? Decrease in the size or spread of
    Confer with physician or other health care if pain or swelling of legs, shortness of breath, breast cancer. Observable effects
    professional regarding analgesics. This transient weakness, sleepiness, confusion, nausea, of therapy may not be seen for 4-
    pain usually resolves despite continued therapy vomiting, weight gain, dizziness, headache, 10 wk after initiation
    loss of appetite, or blurred vision occurs.
    Patient should also report menstrual
    irregularities, vaginal bleeding, pelvic pain or
    pressure

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